1R-Dapagliflozin

Name: 1R-Dapagliflozin
Brand: Vaqora Chemicals
SKU: VQ-004291

About 1R-Dapagliflozin

1R-Dapagliflozin (CAS 1373321-04-0) is an impurity of Dapagliflozin offered by Vaqora Chemicals with a typical assay of 99%. The compound has the formula C21H25ClO6, corresponding to a molecular weight of 408.9 g/mol. The IUPAC name is (2R,3R,4R,5S,6R)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol. Common synonyms include Dapagliflozin Alpha-Isomer and Dapagliflozin |A-isomer.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This Dapagliflozin impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 1R-Dapagliflozin in 10 mg, 25 mg and 50 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Dapagliflozin

View every impurity, metabolite and intermediate we list for Dapagliflozin.

Dapagliflozin impurities

Specifications & identifiers

Chemical identifiers
Product name	1R-Dapagliflozin
Catalogue No.	VQ-004291
CAS Number	1373321-04-0
IUPAC name	(2R,3R,4R,5S,6R)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol
Molecular formula	C₂₁H₂₅ClO₆
Molecular weight	408.9 g/mol
Exact mass	408.134
Grade	Reference Standard
Purity / assay	99%
HSN code	38229090
InChIKey	JVHXJTBJCFBINQ-YMQHIKHWSA-N
SMILES	CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)Cl
PubChem CID	73014129

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	4 / 6
TPSA	99.4 Å²
Synonyms	(1R)-1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-Glucitol, Dapagliflozin Alpha-Isomer, Dapagliflozin, A-isomer, Dapagliflozin, (1R)-, D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, (1R)-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1R-Dapagliflozin?

The CAS Registry Number of 1R-Dapagliflozin is 1373321-04-0. It is also known as (1R)-1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-Glucitol, Dapagliflozin Alpha-Isomer, Dapagliflozin.

What is the molecular formula and molecular weight of 1R-Dapagliflozin?

1R-Dapagliflozin has the molecular formula C21H25ClO6 and a molecular weight of 408.9 g/mol. Its IUPAC name is (2R,3R,4R,5S,6R)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol.

What is 1R-Dapagliflozin used for?

1R-Dapagliflozin is supplied as a characterised reference material related to Dapagliflozin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1R-Dapagliflozin can I order?

We supply 1R-Dapagliflozin in Reference Standard (99%) grade, in 10 mg, 25 mg, 50 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1R-Dapagliflozin?

Yes. Every lot of 1R-Dapagliflozin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1R-Dapagliflozin be shipped internationally?

Yes. 1R-Dapagliflozin is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.