10-Deazaaminopterin

Name: 10-Deazaaminopterin
Brand: Vaqora Chemicals
SKU: VQ-041574

About 10-Deazaaminopterin

Listed under CAS 52454-37-2, 10-Deazaaminopterin is an impurity of Pralatrexate available from Vaqora Chemicals. Its molecular formula is C20H21N7O5 and its molecular weight is 439.4 g/mol. Its systematic (IUPAC) name is (2S)-2-[[4-[2-(2,4-diaminopteridin-6-yl)ethyl]benzoyl]amino]pentanedioic acid. Alternative names: 10-Deazaminopterin and GNF-PF-173.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Pralatrexate to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer 10-Deazaaminopterin in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Pralatrexate

View every impurity, metabolite and intermediate we list for Pralatrexate.

Pralatrexate impurities

Specifications & identifiers

Chemical identifiers
Product name	10-Deazaaminopterin
Catalogue No.	VQ-041574
CAS Number	52454-37-2
IUPAC name	(2S)-2-[[4-[2-(2,4-diaminopteridin-6-yl)ethyl]benzoyl]amino]pentanedioic acid
Molecular formula	C₂₀H₂₁N₇O₅
Molecular weight	439.4 g/mol
Exact mass	439.1604
Grade	Reference Standard
HSN code	38229090
InChIKey	LGFLRHWJJKLPCC-ZDUSSCGKSA-N
SMILES	C1=CC(=CC=C1CCC2=CN=C3C(=N2)C(=NC(=N3)N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)O
PubChem CID	100516

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.3
H-bond donors / acceptors	5 / 11
TPSA	207 Å²
Synonyms	10-Deazaminopterin, L-Glutamic acid, N-(4-(2-(2,4-diamino-6-pteridinyl)ethyl)benzoyl)-, GNF-PF-173, (4-(2-(2,4-diaminopteridin-6-yl)ethyl)benzoyl)-L-glutamic acid, 10-DAM, (S)-2-(4-(2-(2,4-Diaminopteridin-6-yl)ethyl)benzamido)pentanedioic acid, 2-[[4-[2-(2,4-diaminopteridin-6-yl)ethyl]benzoyl]amino]pentanedioic acid, (S)-2-{4-[2-(2,4-Diamino-pteridin-6-yl)-ethyl]-benzoylamino}-pentanedioic acid

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 10-Deazaaminopterin?

The CAS Registry Number of 10-Deazaaminopterin is 52454-37-2. It is also known as 10-Deazaminopterin, L-Glutamic acid, N-(4-(2-(2,4-diamino-6-pteridinyl)ethyl)benzoyl)-, GNF-PF-173.

What is the molecular formula and molecular weight of 10-Deazaaminopterin?

10-Deazaaminopterin has the molecular formula C20H21N7O5 and a molecular weight of 439.4 g/mol. Its IUPAC name is (2S)-2-[[4-[2-(2,4-diaminopteridin-6-yl)ethyl]benzoyl]amino]pentanedioic acid.

What is 10-Deazaaminopterin used for?

10-Deazaaminopterin is supplied as a characterised reference material related to Pralatrexate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 10-Deazaaminopterin can I order?

We supply 10-Deazaaminopterin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 10-Deazaaminopterin?

Yes. Every lot of 10-Deazaaminopterin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 10-Deazaaminopterin be shipped internationally?

Yes. We export 10-Deazaaminopterin worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.