1,2,4-Trifluorobenzene

Name: 1,2,4-Trifluorobenzene
Brand: Vaqora Chemicals
SKU: VQ-012816

About 1,2,4-Trifluorobenzene

Listed under CAS 367-23-7, 1,2,4-Trifluorobenzene is a process intermediate or related compound of Sitagliptin available from Vaqora Chemicals. With the molecular formula C6H3F3, it has a molar mass of 132.08 g/mol. Alternative names: 1,3,4-Trifluorobenzene and Benzene, 1,2,4-trifluoro-.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 4 hazard statements. Review the Safety Data Sheet before use.

It is a process intermediate or related compound in the synthesis of Sitagliptin, useful for route development, impurity fate-and-purge studies and analytical method development. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 1,2,4-Trifluorobenzene in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Sitagliptin

View every impurity, metabolite and intermediate we list for Sitagliptin.

Sitagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	1,2,4-Trifluorobenzene
Catalogue No.	VQ-012816
CAS Number	367-23-7
Other CAS	18497-72-8, 184590-95-2
IUPAC name	1,2,4-trifluorobenzene
Molecular formula	C₆H₃F₃
Molecular weight	132.08 g/mol
Exact mass	132.0187
Grade	Reference Standard
InChIKey	PEBWOGPSYUIOBP-UHFFFAOYSA-N
SMILES	C1=CC(=C(C=C1F)F)F
PubChem CID	67773

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	0 / 3
TPSA	0 Å²
Synonyms	1,3,4-Trifluorobenzene, Benzene, 1,2,4-trifluoro-, 1,2,5-Trifluorobenzene, 1,4-Trifluorobenzene, Benzene,2,4-trifluoro-, 1,2,4-Trifluorobenzene #, 1,4-Trifluorobenzene, misnomer, 1,2,4-Trifluorobenzene, 98%

Safety & hazard information (GHS)

Flammable

Harmful / irritant

Signal word: Danger

Hazard statements

H225Highly flammable liquid and vapor
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P210, P233, P240, P241, P242, P243, P261, P264, P264 + P265, P271, P280, P302 + P352, P303 + P361 + P353, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P370 + P378, P403 + P233, P403 + P235, P405

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1,2,4-Trifluorobenzene?

The CAS Registry Number of 1,2,4-Trifluorobenzene is 367-23-7. It is also known as 1,3,4-Trifluorobenzene, Benzene, 1,2,4-trifluoro-, 1,2,5-Trifluorobenzene.

What is the molecular formula and molecular weight of 1,2,4-Trifluorobenzene?

1,2,4-Trifluorobenzene has the molecular formula C6H3F3 and a molecular weight of 132.08 g/mol. Its IUPAC name is 1,2,4-trifluorobenzene.

What is 1,2,4-Trifluorobenzene used for?

1,2,4-Trifluorobenzene is supplied as a characterised reference material related to Sitagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1,2,4-Trifluorobenzene can I order?

We supply 1,2,4-Trifluorobenzene in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1,2,4-Trifluorobenzene?

Yes. Every lot of 1,2,4-Trifluorobenzene is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1,2,4-Trifluorobenzene be shipped internationally?

Yes. 1,2,4-Trifluorobenzene is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.