Sitagliptin WS

Name: Sitagliptin WS
Brand: Vaqora Chemicals
SKU: VQ-007760

About Sitagliptin WS

Sitagliptin WS (CAS 486460-32-6) is a high-purity reference standard of Sitagliptin offered by Vaqora Chemicals. Its molecular formula is C16H15F6N5O and its molecular weight is 407.31 g/mol. Common synonyms include Sitagliptin and sitagliptine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 3 hazard statements. Review the Safety Data Sheet before use.

As a reference sample of Sitagliptin, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Sitagliptin WS in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Sitagliptin

View every impurity, metabolite and intermediate we list for Sitagliptin.

Sitagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	Sitagliptin WS
Catalogue No.	VQ-007760
CAS Number	486460-32-6
Other CAS	654671-78-0, 486459-71-6, 862156-92-1
IUPAC name	(3R)-3-amino-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one
Molecular formula	C₁₆H₁₅F₆N₅O
Molecular weight	407.31 g/mol
Exact mass	407.1181
Grade	Reference Standard
HSN code	38229090
InChIKey	MFFMDFFZMYYVKS-SECBINFHSA-N
SMILES	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N
PubChem CID	4369359

Physical properties
Physical form	Solid
LogP (XLogP3)	0.7
H-bond donors / acceptors	1 / 10
TPSA	77 Å²
Synonyms	Sitagliptin, sitagliptine, LEZ-763, Sitagliptin (Metformin,MK-0431), LEZ 763, Sitagliptin (13), SitagliptinMK0431, MK0431, Sitagliptin (USAN/INN), EX-A2816, WHO 8692, Sitagliptin 100 microg/mL in Acetonitrile

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H318Causes serious eye damage
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P260, P264, P264 + P265, P270, P280, P301 + P317, P305 + P354 + P338, P317, P319, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 486460-32-6

IP/BP/USP

Sitagliptin

CAS: 486460-32-6
Formula: C₁₆H₁₅F₆N₅O
MW: 407.31 g/mol

VQ-004146

Frequently asked questions

What is the CAS number of Sitagliptin WS?

The CAS Registry Number of Sitagliptin WS is 486460-32-6. It is also known as Sitagliptin, sitagliptine, LEZ-763.

What is the molecular formula and molecular weight of Sitagliptin WS?

Sitagliptin WS has the molecular formula C16H15F6N5O and a molecular weight of 407.31 g/mol. Its IUPAC name is (3R)-3-amino-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one.

What is Sitagliptin WS used for?

Sitagliptin WS is supplied as a characterised reference material related to Sitagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sitagliptin WS can I order?

We supply Sitagliptin WS in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sitagliptin WS?

Yes. Every lot of Sitagliptin WS is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sitagliptin WS be shipped internationally?

Yes. Sitagliptin WS is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.