1,4-Dioxane-D8

Name: 1,4-Dioxane-D8
Brand: Vaqora Chemicals
SKU: VQ-052426

About 1,4-Dioxane-D8

Listed under CAS 17647-74-4, 1,4-Dioxane-D8 is a stable isotope labelled standard available from Vaqora Chemicals. Formula C4H8O2, molecular weight 96.15 g/mol. Its systematic (IUPAC) name is 2,2,3,3,5,5,6,6-octadeuterio-1,4-dioxane. Alternative names: 1,4-Dioxane-(2LH8) and 1,4-dioxane-[2LH8].

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 1,4-Dioxane-D8 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	1,4-Dioxane-D8
Catalogue No.	VQ-052426
CAS Number	17647-74-4
IUPAC name	2,2,3,3,5,5,6,6-octadeuterio-1,4-dioxane
Molecular formula	C₄H₈O₂
Molecular weight	96.15 g/mol
Exact mass	96.1026
Grade	Reference Standard
HSN code	38229090
InChIKey	RYHBNJHYFVUHQT-SVYQBANQSA-N
SMILES	[2H]C1(C(OC(C(O1)([2H])[2H])([2H])[2H])([2H])[2H])[2H]
PubChem CID	87209

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.3
H-bond donors / acceptors	0 / 2
TPSA	18.5 Å²
Synonyms	1,4-Dioxane-(2LH8), 1,4-dioxane-[2LH8], 1,4-Dioxane-2,2,3,3,5,5,6,6-d8, Dioxane D8, 1,4-dioxane-d8 (p-dioxane), TMIJ-0355, (~2~H_8_)-1,4-Dioxane

Safety & hazard information (GHS)

Flammable

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H225Highly flammable liquid and vapor
H319Causes serious eye irritation
H335May cause respiratory irritation
H351Suspected of causing cancer

Precautionary statements: P203, P210, P233, P240, P241, P242, P243, P261, P264 + P265, P271, P280, P303 + P361 + P353, P304 + P340, P305 + P351 + P338, P318, P319, P337 + P317, P370 + P378, P403 + P233, P403 + P235, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1,4-Dioxane-D8?

The CAS Registry Number of 1,4-Dioxane-D8 is 17647-74-4. It is also known as 1,4-Dioxane-(2LH8), 1,4-dioxane-[2LH8], 1,4-Dioxane-2,2,3,3,5,5,6,6-d8.

What is the molecular formula and molecular weight of 1,4-Dioxane-D8?

1,4-Dioxane-D8 has the molecular formula C4H8O2 and a molecular weight of 96.15 g/mol. Its IUPAC name is 2,2,3,3,5,5,6,6-octadeuterio-1,4-dioxane.

Which grade and pack sizes of 1,4-Dioxane-D8 can I order?

We supply 1,4-Dioxane-D8 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1,4-Dioxane-D8?

Yes. Every lot of 1,4-Dioxane-D8 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1,4-Dioxane-D8 be shipped internationally?

Yes. 1,4-Dioxane-D8 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.