1α,25-Dihydroxyprevitamin D3

Name: 1α,25-Dihydroxyprevitamin D3
Brand: Vaqora Chemicals
SKU: VQ-047667

About 1α,25-Dihydroxyprevitamin D3

Vaqora Chemicals supplies 1α,25-Dihydroxyprevitamin D3, an impurity of Calcitriol registered under CAS number 57102-09-7. Formula C27H44O3, molecular weight 416.6 g/mol. Common synonyms include 1,25-Dihydroxytachysterol and 1alpha,25-Dihydroxy-previtamin D3.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Calcitriol impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Calcitriol

View every impurity, metabolite and intermediate we list for Calcitriol.

Calcitriol impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	1α,25-Dihydroxyprevitamin D3
Catalogue No.	VQ-047667
CAS Number	57102-09-7
IUPAC name	(1S,3R)-5-[(Z)-2-[(1R,3aR,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-1,2,3,3a,6,7-hexahydroinden-4-yl]ethenyl]-4-methylcyclohex-4-ene-1,3-diol
Molecular formula	C₂₇H₄₄O₃
Molecular weight	416.6 g/mol
Exact mass	416.329
Grade	Reference Standard
HSN code	38229090
InChIKey	DOIZGAFWGREMOD-BJGFKTPISA-N
SMILES	CC1=C(C[C@@H](C[C@H]1O)O)/C=C\C2=CCC[C@]3([C@H]2CC[C@@H]3[C@H](C)CCCC(C)(C)O)C
PubChem CID	6438507

Physical properties
Physical form	Solid
LogP (XLogP3)	4.8
H-bond donors / acceptors	3 / 3
TPSA	60.7 Å²
Synonyms	1,25-Dihydroxytachysterol, 9,10-secocholesta-5(10),6,8-triene-1,3,25-triol, (1 alpha,3 beta,6Z)-, 1alpha,25-Dihydroxy-previtamin D3, Pre-Calcitriol, (4E,6Z,8Z)-(1S,3R)-4-methyl-9,10-seco-5,7,10(19)-cholestatriene-1,3,25-triol, 9,10-Secocholesta-5(10),6,8-triene-1,3,25-triol, (1alpha,3beta,6Z)-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1α,25-Dihydroxyprevitamin D3?

The CAS Registry Number of 1α,25-Dihydroxyprevitamin D3 is 57102-09-7. It is also known as 1,25-Dihydroxytachysterol, 9,10-secocholesta-5(10),6,8-triene-1,3,25-triol, (1 alpha,3 beta,6Z)-, 1alpha,25-Dihydroxy-previtamin D3.

What is the molecular formula and molecular weight of 1α,25-Dihydroxyprevitamin D3?

1α,25-Dihydroxyprevitamin D3 has the molecular formula C27H44O3 and a molecular weight of 416.6 g/mol. Its IUPAC name is (1S,3R)-5-[(Z)-2-[(1R,3aR,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-1,2,3,3a,6,7-hexahydroinden-4-yl]ethenyl]-4-methylcyclohex-4-ene-1,3-diol.

What is 1α,25-Dihydroxyprevitamin D3 used for?

1α,25-Dihydroxyprevitamin D3 is supplied as a characterised reference material related to Calcitriol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1α,25-Dihydroxyprevitamin D3 can I order?

We supply 1α,25-Dihydroxyprevitamin D3 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1α,25-Dihydroxyprevitamin D3?

Yes. Every lot of 1α,25-Dihydroxyprevitamin D3 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1α,25-Dihydroxyprevitamin D3 be shipped internationally?

Yes. We export 1α,25-Dihydroxyprevitamin D3 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.