(1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1… 361440-67-7

Name: (1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester
Brand: Vaqora Chemicals
SKU: VQ-042107

About (1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester

Listed under CAS 361440-67-7, (1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester is an impurity of Saxagliptin available from Vaqora Chemicals. Its molecular formula is C11H18N2O3 and its molecular weight is 226.27 g/mol. The IUPAC name is tert-butyl (1S,3S,5S)-3-carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate. Common synonyms include N-Boc-L-cis-4,5-Methanoprolineamide and N-Boc-cis-4,5-Methano-L-prolinamide.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Saxagliptin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Saxagliptin

View every impurity, metabolite and intermediate we list for Saxagliptin.

Saxagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	(1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester
Catalogue No.	VQ-042107
CAS Number	361440-67-7
IUPAC name	tert-butyl (1S,3S,5S)-3-carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate
Molecular formula	C₁₁H₁₈N₂O₃
Molecular weight	226.27 g/mol
Exact mass	226.1317
Grade	Reference Standard
HSN code	38229090
InChIKey	VLAGXRRGXCNITB-FXQIFTODSA-N
SMILES	CC(C)(C)OC(=O)N1[C@H]2C[C@H]2C[C@H]1C(=O)N
PubChem CID	51358357

Physical properties
Physical form	Solid
LogP (XLogP3)	0.7
H-bond donors / acceptors	1 / 3
TPSA	72.6 Å²
Synonyms	N-Boc-L-cis-4,5-Methanoprolineamide, 1,1-Dimethylethyl (1S,3S,5S)-3-(aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylate, 1,1-Dimethylethyl (1S,3S,5S)-3-(aminocarbonyl)-2-azabicyclo(3.1.0)hexane-2-carboxylate, tert-butyl (1S,3S,5S)-3-carbamoyl-2-azabicyclo(3.1.0)hexane-2-carboxylate, (1S,3S,5S)-tert-Butyl 3-carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate, rel-(1S,3S,5S)-tert-Butyl 3-carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate, (1S,3S,5S)-2-Boc-2-azabicyclo-[3.1.0]hexane-3-carboxamide, N-Boc-cis-4,5-Methano-L-prolinamide, (1S,3S,5S)-2-Boc-3-carbamoyl-2-azabicyclo[3.1.0]hexane

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester?

The CAS Registry Number of (1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester is 361440-67-7. It is also known as N-Boc-L-cis-4,5-Methanoprolineamide, 1,1-Dimethylethyl (1S,3S,5S)-3-(aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylate, 1,1-Dimethylethyl (1S,3S,5S)-3-(aminocarbonyl)-2-azabicyclo(3.1.0)hexane-2-carboxylate.

What is the molecular formula and molecular weight of (1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester?

(1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester has the molecular formula C11H18N2O3 and a molecular weight of 226.27 g/mol. Its IUPAC name is tert-butyl (1S,3S,5S)-3-carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate.

What is (1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester used for?

(1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester is supplied as a characterised reference material related to Saxagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester can I order?

We supply (1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester?

Yes. Every lot of (1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester be shipped internationally?

Yes. We export (1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.