2-(4-Boc-Piperazino)-5-Bromopyridine

Name: 2-(4-Boc-Piperazino)-5-Bromopyridine
Brand: Vaqora Chemicals
SKU: VQ-033211

About 2-(4-Boc-Piperazino)-5-Bromopyridine

2-(4-Boc-Piperazino)-5-Bromopyridine (CAS 153747-97-8) is an impurity of Palbociclib offered by Vaqora Chemicals. With the molecular formula C14H20BrN3O2, it has a molar mass of 342.23 g/mol. Systematically, it is named tert-butyl 4-(5-bromo-2-pyridinyl)piperazine-1-carboxylate. Alternative names: 4-Boc-1-(5-bromo-2-pyridyl)piperazine and 5-Bromo-2-[4-(N-boc)piperazin-1-yl]pyridine.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 4 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Palbociclib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Palbociclib

View every impurity, metabolite and intermediate we list for Palbociclib.

Palbociclib impurities

Specifications & identifiers

Chemical identifiers
Product name	2-(4-Boc-Piperazino)-5-Bromopyridine
Catalogue No.	VQ-033211
CAS Number	153747-97-8
IUPAC name	tert-butyl 4-(5-bromo-2-pyridinyl)piperazine-1-carboxylate
Molecular formula	C₁₄H₂₀BrN₃O₂
Molecular weight	342.23 g/mol
Exact mass	341.0739
Grade	Reference Standard
HSN code	38229090
InChIKey	DSLVSFMWCDGZIL-UHFFFAOYSA-N
SMILES	CC(C)(C)OC(=O)N1CCN(CC1)C2=NC=C(C=C2)Br
PubChem CID	11244775

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	0 / 4
TPSA	45.7 Å²
Synonyms	4-Boc-1-(5-bromo-2-pyridyl)piperazine, Tert-butyl 4-(5-bromopyridin-2-yl)piperazine-1-carboxylate, 5-Bromo-2-(4-tert-butoxycarbonylpiperazin-1-yl)pyridine, 5-Bromo-2-[4-(N-boc)piperazin-1-yl]pyridine, 4-(5-Bromo-pyridin-2-yl)-piperazine-1-carboxylic acid tert-butyl ester, CS-M2405, EX-A3898, 4-(5-Bromopyridin-2-yl)piperazine-1-carboxylic acid tert-butyl ester, tert-Butyl 4-(5-bromo-2-pyridinyl)-1-piperazinecarboxylate, tert-butyl 4-(5-bromopyridin-2-yl)piperazin-1-carboxylate, Tert-butyl4-(5-bromopyridin-2-yl)piperazine-1-carboxylate, tert-Butyl 4-(5'-bromopyrid-2'-yl)piperazine-1-carboxylate

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-(4-Boc-Piperazino)-5-Bromopyridine?

The CAS Registry Number of 2-(4-Boc-Piperazino)-5-Bromopyridine is 153747-97-8. It is also known as 4-Boc-1-(5-bromo-2-pyridyl)piperazine, Tert-butyl 4-(5-bromopyridin-2-yl)piperazine-1-carboxylate, 5-Bromo-2-(4-tert-butoxycarbonylpiperazin-1-yl)pyridine.

What is the molecular formula and molecular weight of 2-(4-Boc-Piperazino)-5-Bromopyridine?

2-(4-Boc-Piperazino)-5-Bromopyridine has the molecular formula C14H20BrN3O2 and a molecular weight of 342.23 g/mol. Its IUPAC name is tert-butyl 4-(5-bromo-2-pyridinyl)piperazine-1-carboxylate.

What is 2-(4-Boc-Piperazino)-5-Bromopyridine used for?

2-(4-Boc-Piperazino)-5-Bromopyridine is supplied as a characterised reference material related to Palbociclib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-(4-Boc-Piperazino)-5-Bromopyridine can I order?

We supply 2-(4-Boc-Piperazino)-5-Bromopyridine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-(4-Boc-Piperazino)-5-Bromopyridine?

Yes. Every lot of 2-(4-Boc-Piperazino)-5-Bromopyridine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-(4-Boc-Piperazino)-5-Bromopyridine be shipped internationally?

Yes. 2-(4-Boc-Piperazino)-5-Bromopyridine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.