2-Chloro-4-methylsulfonylbenzoic acid

Name: 2-Chloro-4-methylsulfonylbenzoic acid
Brand: Vaqora Chemicals
SKU: VQ-045179

About 2-Chloro-4-methylsulfonylbenzoic acid

Vaqora Chemicals supplies 2-Chloro-4-methylsulfonylbenzoic acid, an impurity of Vismodegib registered under CAS number 53250-83-2. With the molecular formula C8H7ClO4S, it has a molar mass of 234.66 g/mol. It is also known as Benzoic acid, 2-chloro-4-(methylsulfonyl)- or 2-chloro-4-methylsulphonylbenzoic acid.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Vismodegib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer 2-Chloro-4-methylsulfonylbenzoic acid in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Vismodegib

View every impurity, metabolite and intermediate we list for Vismodegib.

Vismodegib impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Chloro-4-methylsulfonylbenzoic acid
Catalogue No.	VQ-045179
CAS Number	53250-83-2
IUPAC name	2-chloro-4-methylsulfonylbenzoic acid
Molecular formula	C₈H₇ClO₄S
Molecular weight	234.66 g/mol
Exact mass	233.9754
Grade	Reference Standard
HSN code	38229090
InChIKey	CTTWSFIIFMWHLQ-UHFFFAOYSA-N
SMILES	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl
PubChem CID	735863

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	1 / 4
TPSA	79.8 Å²
Synonyms	Benzoic acid, 2-chloro-4-(methylsulfonyl)-, 2-chloro-4-methylsulphonylbenzoic acid, 2-chloro-4-methanesulfonylbenzoic acid, 2-chloro-4-(methylsulphonyl)benzoic acid, 2-Chloro-4-(methanesulfonyl)benzoic acid, 2-Chloro-4-MethanesulfonYl-Benzoic Acid, 2-chloro-4-methanesulfonyl benzoic acid

Safety & hazard information (GHS)

Corrosive

Signal word: Danger

Hazard statements

H318Causes serious eye damage

Precautionary statements: P264 + P265, P280, P305 + P354 + P338, P317

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Chloro-4-methylsulfonylbenzoic acid?

The CAS Registry Number of 2-Chloro-4-methylsulfonylbenzoic acid is 53250-83-2. It is also known as Benzoic acid, 2-chloro-4-(methylsulfonyl)-, 2-chloro-4-methylsulphonylbenzoic acid, 2-chloro-4-methanesulfonylbenzoic acid.

What is the molecular formula and molecular weight of 2-Chloro-4-methylsulfonylbenzoic acid?

2-Chloro-4-methylsulfonylbenzoic acid has the molecular formula C8H7ClO4S and a molecular weight of 234.66 g/mol. Its IUPAC name is 2-chloro-4-methylsulfonylbenzoic acid.

What is 2-Chloro-4-methylsulfonylbenzoic acid used for?

2-Chloro-4-methylsulfonylbenzoic acid is supplied as a characterised reference material related to Vismodegib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Chloro-4-methylsulfonylbenzoic acid can I order?

We supply 2-Chloro-4-methylsulfonylbenzoic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Chloro-4-methylsulfonylbenzoic acid?

Yes. Every lot of 2-Chloro-4-methylsulfonylbenzoic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Chloro-4-methylsulfonylbenzoic acid be shipped internationally?

Yes. 2-Chloro-4-methylsulfonylbenzoic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.