4-Chloro-2-(methylsulfonyl)benzoic Acid

Name: 4-Chloro-2-(methylsulfonyl)benzoic Acid
Brand: Vaqora Chemicals
SKU: VQ-042917

About 4-Chloro-2-(methylsulfonyl)benzoic Acid

Vaqora Chemicals supplies 4-Chloro-2-(methylsulfonyl)benzoic Acid, an impurity of Vismodegib registered under CAS number 142994-03-4. The compound has the formula C8H7ClO4S, corresponding to a molecular weight of 234.66 g/mol. Common synonyms include 4-chloro-2-(methylsulphonyl)benzoic acid and Benzoic acid,4-chloro-2-(methylsulfonyl)-.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Vismodegib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 4-Chloro-2-(methylsulfonyl)benzoic Acid in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Vismodegib

View every impurity, metabolite and intermediate we list for Vismodegib.

Vismodegib impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Chloro-2-(methylsulfonyl)benzoic Acid
Catalogue No.	VQ-042917
CAS Number	142994-03-4
IUPAC name	4-chloro-2-methylsulfonylbenzoic acid
Molecular formula	C₈H₇ClO₄S
Molecular weight	234.66 g/mol
Exact mass	233.9754
Grade	Reference Standard
HSN code	38229090
InChIKey	VACSKKVZIVNUDP-UHFFFAOYSA-N
SMILES	CS(=O)(=O)C1=C(C=CC(=C1)Cl)C(=O)O
PubChem CID	2761055

Physical properties
Physical form	Solid
LogP (XLogP3)	1.3
H-bond donors / acceptors	1 / 4
TPSA	79.8 Å²
Synonyms	4-chloro-2-(methylsulphonyl)benzoic acid, Benzoic acid,4-chloro-2-(methylsulfonyl)-, 4-chloro-2-methanesulfonylbenzoic acid, mono-mesyl-monochloro benzoic acid, 4-Chloro-2-(methanesulfonyl)benzoic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Chloro-2-(methylsulfonyl)benzoic Acid?

The CAS Registry Number of 4-Chloro-2-(methylsulfonyl)benzoic Acid is 142994-03-4. It is also known as 4-chloro-2-(methylsulphonyl)benzoic acid, Benzoic acid,4-chloro-2-(methylsulfonyl)-, 4-chloro-2-methanesulfonylbenzoic acid.

What is the molecular formula and molecular weight of 4-Chloro-2-(methylsulfonyl)benzoic Acid?

4-Chloro-2-(methylsulfonyl)benzoic Acid has the molecular formula C8H7ClO4S and a molecular weight of 234.66 g/mol. Its IUPAC name is 4-chloro-2-methylsulfonylbenzoic acid.

What is 4-Chloro-2-(methylsulfonyl)benzoic Acid used for?

4-Chloro-2-(methylsulfonyl)benzoic Acid is supplied as a characterised reference material related to Vismodegib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Chloro-2-(methylsulfonyl)benzoic Acid can I order?

We supply 4-Chloro-2-(methylsulfonyl)benzoic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Chloro-2-(methylsulfonyl)benzoic Acid?

Yes. Every lot of 4-Chloro-2-(methylsulfonyl)benzoic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Chloro-2-(methylsulfonyl)benzoic Acid be shipped internationally?

Yes. 4-Chloro-2-(methylsulfonyl)benzoic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.