2-Chloro-4(3H)-pyrimidinone

Name: 2-Chloro-4(3H)-pyrimidinone
Brand: Vaqora Chemicals
SKU: VQ-012944

About 2-Chloro-4(3H)-pyrimidinone

2-Chloro-4(3H)-pyrimidinone (CAS 55873-09-1) is a process intermediate or related compound of Pazopanib offered by Vaqora Chemicals. With the molecular formula C4H3ClN2O, it has a molar mass of 130.53 g/mol. Its systematic (IUPAC) name is 2-chloro-1H-pyrimidin-6-one. Common synonyms include 2-Chloro-4-hydroxypyrimidine and 2-Chloropyrimidin-4-ol.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Process chemists and analysts use it when developing synthetic routes to Pazopanib, tracking process-related impurities and validating analytical methods. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 2-Chloro-4(3H)-pyrimidinone is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Pazopanib

View every impurity, metabolite and intermediate we list for Pazopanib.

Pazopanib impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Chloro-4(3H)-pyrimidinone
Catalogue No.	VQ-012944
CAS Number	55873-09-1
IUPAC name	2-chloro-1H-pyrimidin-6-one
Molecular formula	C₄H₃ClN₂O
Molecular weight	130.53 g/mol
Exact mass	129.9934
Grade	Reference Standard
HSN code	2933
InChIKey	FETSYNXZMUAONO-UHFFFAOYSA-N
SMILES	C1=CN=C(NC1=O)Cl
PubChem CID	13678541

Physical properties
Physical form	Solid
LogP (XLogP3)	0.6
H-bond donors / acceptors	1 / 2
TPSA	41.5 Å²
Synonyms	2-Chloro-4-hydroxypyrimidine, 2-Chloropyrimidin-4-ol, 2-Chloropyrimidin-4(3H)-one, 2-Chloro-4(1H)-pyrimidinone, Chlor- 6-Oxypyrimidin, 4(3H)-Pyrimidinone,2-chloro-, 4(1H)-Pyrimidino, 4(1H)-Pyrimidinone, 2-chloro-, 4(3H)-Pyrimidinone, 2-chloro-, 2-chloro-3,4-dihydropyrimidin-4-one

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Chloro-4(3H)-pyrimidinone?

The CAS Registry Number of 2-Chloro-4(3H)-pyrimidinone is 55873-09-1. It is also known as 2-Chloro-4-hydroxypyrimidine, 2-Chloropyrimidin-4-ol, 2-Chloropyrimidin-4(3H)-one.

What is the molecular formula and molecular weight of 2-Chloro-4(3H)-pyrimidinone?

2-Chloro-4(3H)-pyrimidinone has the molecular formula C4H3ClN2O and a molecular weight of 130.53 g/mol. Its IUPAC name is 2-chloro-1H-pyrimidin-6-one.

What is 2-Chloro-4(3H)-pyrimidinone used for?

2-Chloro-4(3H)-pyrimidinone is supplied as a characterised reference material related to Pazopanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Chloro-4(3H)-pyrimidinone can I order?

We supply 2-Chloro-4(3H)-pyrimidinone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Chloro-4(3H)-pyrimidinone?

Yes. Every lot of 2-Chloro-4(3H)-pyrimidinone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Chloro-4(3H)-pyrimidinone be shipped internationally?

Yes. We export 2-Chloro-4(3H)-pyrimidinone worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.