2-Chlorothiophene

Name: 2-Chlorothiophene
Brand: Vaqora Chemicals
SKU: VQ-033600

About 2-Chlorothiophene

Vaqora Chemicals supplies 2-Chlorothiophene, an impurity of Rivaroxaban registered under CAS number 96-43-5. Its molecular formula is C4H3ClS and its molecular weight is 118.59 g/mol. Common synonyms include 2-Thienyl chloride and Thiophene, 2-chloro-.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Rivaroxaban to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 2-Chlorothiophene in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Rivaroxaban

View every impurity, metabolite and intermediate we list for Rivaroxaban.

Rivaroxaban impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Chlorothiophene
Catalogue No.	VQ-033600
CAS Number	96-43-5
IUPAC name	2-chlorothiophene
Molecular formula	C₄H₃ClS
Molecular weight	118.59 g/mol
Exact mass	117.9644
Grade	Reference Standard
HSN code	38229090
InChIKey	GSFNQBFZFXUTBN-UHFFFAOYSA-N
SMILES	C1=CSC(=C1)Cl
PubChem CID	7299

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	0 / 1
TPSA	28.2 Å²
Synonyms	2-Thienyl chloride, Thiophene, 2-chloro-, chlorothiophene, Thienyl chloride, 5-chlorothiophene

Safety & hazard information (GHS)

Flammable

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H225Highly flammable liquid and vapor
H226Flammable liquid and vapor
H301Toxic if swallowed
H311Toxic in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H330Fatal if inhaled
H335May cause respiratory irritation

Precautionary statements: P210, P233, P240, P241, P242, P243, P260, P261, P262, P264, P264 + P265, P270, P271, P280, P284, P301 + P316, P302 + P352, P303 + P361 + P353, P304 + P340, P305 + P351 + P338, P316, P319, P320, P321

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Chlorothiophene?

The CAS Registry Number of 2-Chlorothiophene is 96-43-5. It is also known as 2-Thienyl chloride, Thiophene, 2-chloro-, chlorothiophene.

What is the molecular formula and molecular weight of 2-Chlorothiophene?

2-Chlorothiophene has the molecular formula C4H3ClS and a molecular weight of 118.59 g/mol. Its IUPAC name is 2-chlorothiophene.

What is 2-Chlorothiophene used for?

2-Chlorothiophene is supplied as a characterised reference material related to Rivaroxaban. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Chlorothiophene can I order?

We supply 2-Chlorothiophene in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Chlorothiophene?

Yes. Every lot of 2-Chlorothiophene is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Chlorothiophene be shipped internationally?

Yes. 2-Chlorothiophene is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.