N-(3-Chloro-2-hydroxypropyl)-phthalimide

Name: N-(3-Chloro-2-hydroxypropyl)-phthalimide
Brand: Vaqora Chemicals
SKU: VQ-033598

About N-(3-Chloro-2-hydroxypropyl)-phthalimide

Listed under CAS 19667-37-9, N-(3-Chloro-2-hydroxypropyl)-phthalimide is a metabolite or degradation product of Rivaroxaban available from Vaqora Chemicals. Formula C11H10ClNO3, molecular weight 239.65 g/mol. Systematically, it is named 2-(3-chloro-2-hydroxypropyl)isoindole-1,3-dione. Common synonyms include 1-chloro-3-phthalimido-2-propanol and 1-Chloro-2-hydroxy-3-phthalimidopropane.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 2 hazard statements. Review the Safety Data Sheet before use.

Analytical teams use this compound to identify metabolites and degradants of Rivaroxaban, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies N-(3-Chloro-2-hydroxypropyl)-phthalimide in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Rivaroxaban

View every impurity, metabolite and intermediate we list for Rivaroxaban.

Rivaroxaban impurities

Specifications & identifiers

Chemical identifiers
Product name	N-(3-Chloro-2-hydroxypropyl)-phthalimide
Catalogue No.	VQ-033598
CAS Number	19667-37-9
IUPAC name	2-(3-chloro-2-hydroxypropyl)isoindole-1,3-dione
Molecular formula	C₁₁H₁₀ClNO₃
Molecular weight	239.65 g/mol
Exact mass	239.0349
Grade	Reference Standard
HSN code	38229090
InChIKey	KBRVYEPWGIQEOF-UHFFFAOYSA-N
SMILES	C1=CC=C2C(=C1)C(=O)N(C2=O)CC(CCl)O
PubChem CID	262103

Physical properties
Physical form	Solid
LogP (XLogP3)	1.5
H-bond donors / acceptors	1 / 3
TPSA	57.6 Å²
Synonyms	2-(3-chloro-2-hydroxypropyl)isoindoline-1,3-dione, 2-(3-chloro-2-hydroxypropyl)-1H-isoindole-1,3(2H)-dione, 2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione, 2-(3-chloro-2-hydroxypropyl)-2,3-dihydro-1H-isoindole-1,3-dione, 1H-Isoindole-1,3(2H)-dione, 2-(3-chloro-2-hydroxypropyl)-, 1-chloro-3-phthalimido-2-propanol, 2-(3-chloro-2-hydroxypropyl)benzo[c]azoline-1,3-dione, 2-(3-Chloro-2-hydroxy-propyl)-isoindole-1,3-dione, 1H-Isoindole-1,3(2H)-dione, 2-(3-chloro-2-hydroxypropyl)-, (S)-, 1H-Isoindole-1,3(2H)-dione,2-(3-chloro-2-hydroxypropyl)-, 1-Chloro-2-hydroxy-3-phthalimidopropane

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P270, P280, P301 + P317, P305 + P351 + P338, P330, P337 + P317, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-(3-Chloro-2-hydroxypropyl)-phthalimide?

The CAS Registry Number of N-(3-Chloro-2-hydroxypropyl)-phthalimide is 19667-37-9. It is also known as 2-(3-chloro-2-hydroxypropyl)isoindoline-1,3-dione, 2-(3-chloro-2-hydroxypropyl)-1H-isoindole-1,3(2H)-dione, 2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione.

What is the molecular formula and molecular weight of N-(3-Chloro-2-hydroxypropyl)-phthalimide?

N-(3-Chloro-2-hydroxypropyl)-phthalimide has the molecular formula C11H10ClNO3 and a molecular weight of 239.65 g/mol. Its IUPAC name is 2-(3-chloro-2-hydroxypropyl)isoindole-1,3-dione.

What is N-(3-Chloro-2-hydroxypropyl)-phthalimide used for?

N-(3-Chloro-2-hydroxypropyl)-phthalimide is supplied as a characterised reference material related to Rivaroxaban. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-(3-Chloro-2-hydroxypropyl)-phthalimide can I order?

We supply N-(3-Chloro-2-hydroxypropyl)-phthalimide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-(3-Chloro-2-hydroxypropyl)-phthalimide?

Yes. Every lot of N-(3-Chloro-2-hydroxypropyl)-phthalimide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-(3-Chloro-2-hydroxypropyl)-phthalimide be shipped internationally?

Yes. N-(3-Chloro-2-hydroxypropyl)-phthalimide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.