2-Methanol Abemaciclib

Name: 2-Methanol Abemaciclib
Brand: Vaqora Chemicals
SKU: VQ-020706

About 2-Methanol Abemaciclib

Listed under CAS 2138499-06-4, 2-Methanol Abemaciclib is a metabolite or degradation product of Abemaciclib available from Vaqora Chemicals. The compound has the formula C27H32F2N8O, corresponding to a molecular weight of 522.6 g/mol. Common synonyms include Abemaciclib metabolite M20 and Two methanol abemaciclib.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Abemaciclib, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 2-Methanol Abemaciclib is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Abemaciclib

View every impurity, metabolite and intermediate we list for Abemaciclib.

Abemaciclib impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Methanol Abemaciclib
Catalogue No.	VQ-020706
CAS Number	2138499-06-4
IUPAC name	[6-[2-[[5-[(4-ethylpiperazin-1-yl)methyl]-2-pyridinyl]amino]-5-fluoropyrimidin-4-yl]-4-fluoro-1-propan-2-ylbenzimidazol-2-yl]methanol
Molecular formula	C₂₇H₃₂F₂N₈O
Molecular weight	522.6 g/mol
Exact mass	522.2667
Grade	Reference Standard
HSN code	38229090
InChIKey	KUJBDJBMXOTNIT-UHFFFAOYSA-N
SMILES	CCN1CCN(CC1)CC2=CN=C(C=C2)NC3=NC=C(C(=N3)C4=CC5=C(C(=C4)F)N=C(N5C(C)C)CO)F
PubChem CID	139600311

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	2 / 10
TPSA	95.2 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Methanol Abemaciclib?

The CAS Registry Number of 2-Methanol Abemaciclib is 2138499-06-4. It is also known as Abemaciclib metabolite M20, Two methanol abemaciclib, CDK4/6-IN-4.

What is the molecular formula and molecular weight of 2-Methanol Abemaciclib?

2-Methanol Abemaciclib has the molecular formula C27H32F2N8O and a molecular weight of 522.6 g/mol. Its IUPAC name is [6-[2-[[5-[(4-ethylpiperazin-1-yl)methyl]-2-pyridinyl]amino]-5-fluoropyrimidin-4-yl]-4-fluoro-1-propan-2-ylbenzimidazol-2-yl]methanol.

What is 2-Methanol Abemaciclib used for?

2-Methanol Abemaciclib is supplied as a characterised reference material related to Abemaciclib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Methanol Abemaciclib can I order?

We supply 2-Methanol Abemaciclib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Methanol Abemaciclib?

Yes. Every lot of 2-Methanol Abemaciclib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Methanol Abemaciclib be shipped internationally?

Yes. We export 2-Methanol Abemaciclib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.