Abemaciclib D5

Name: Abemaciclib D5
Brand: Vaqora Chemicals
SKU: VQ-021375

About Abemaciclib D5

Abemaciclib D5 is a stable isotope labelled analogue related to Abemaciclib carrying the CAS registry number 1809251-51-1. Formula C27H32F2N8, molecular weight 511.6 g/mol. It is also known as Abemaciclib-d5 (N-Ethyl-d5).

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Abemaciclib and related analytes in bioanalytical, pharmacokinetic and impurity studies. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Abemaciclib D5 is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Abemaciclib

View every impurity, metabolite and intermediate we list for Abemaciclib.

Abemaciclib impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Abemaciclib D5
Catalogue No.	VQ-021375
CAS Number	1809251-51-1
IUPAC name	5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)-N-[5-[[4-(1,1,2,2,2-pentadeuterioethyl)piperazin-1-yl]methyl]-2-pyridinyl]pyrimidin-2-amine
Molecular formula	C₂₇H₃₂F₂N₈
Molecular weight	511.6 g/mol
Exact mass	511.3032
Grade	Reference Standard
HSN code	38229090
InChIKey	UZWDCWONPYILKI-RPIBLTHZSA-N
SMILES	[2H]C([2H])([2H])C([2H])([2H])N1CCN(CC1)CC2=CN=C(C=C2)NC3=NC=C(C(=N3)C4=CC5=C(C(=C4)F)N=C(N5C(C)C)C)F
PubChem CID	141504873

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	1 / 9
TPSA	75 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Abemaciclib D5?

The CAS Registry Number of Abemaciclib D5 is 1809251-51-1. It is also known as Abemaciclib-d5 (N-Ethyl-d5).

What is the molecular formula and molecular weight of Abemaciclib D5?

Abemaciclib D5 has the molecular formula C27H32F2N8 and a molecular weight of 511.6 g/mol. Its IUPAC name is 5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)-N-[5-[[4-(1,1,2,2,2-pentadeuterioethyl)piperazin-1-yl]methyl]-2-pyridinyl]pyrimidin-2-amine.

What is Abemaciclib D5 used for?

Abemaciclib D5 is supplied as a characterised reference material related to Abemaciclib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Abemaciclib D5 can I order?

We supply Abemaciclib D5 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Abemaciclib D5?

Yes. Every lot of Abemaciclib D5 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Abemaciclib D5 be shipped internationally?

Yes. We export Abemaciclib D5 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.