21-Carboxy Dexamethasone

Name: 21-Carboxy Dexamethasone
Brand: Vaqora Chemicals
SKU: VQ-022349

About 21-Carboxy Dexamethasone

21-Carboxy Dexamethasone is an impurity of Dexamethasone carrying the CAS registry number 84449-15-0. Its molecular formula is C22H27FO6 and its molecular weight is 406.4 g/mol. It is also known as Dexamethasone Glyoxal Analog or Dexamethasone-21-oic acid.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This Dexamethasone impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 21-Carboxy Dexamethasone in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Dexamethasone

View every impurity, metabolite and intermediate we list for Dexamethasone.

Dexamethasone impurities

Specifications & identifiers

Chemical identifiers
Product name	21-Carboxy Dexamethasone
Catalogue No.	VQ-022349
CAS Number	84449-15-0
IUPAC name	2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoacetic acid
Molecular formula	C₂₂H₂₇FO₆
Molecular weight	406.4 g/mol
Exact mass	406.1792
Grade	Reference Standard
HSN code	38229090
InChIKey	HJQXVITYEPBWQP-LODYHXIVSA-N
SMILES	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)C(=O)O)O)C)O)F)C
PubChem CID	67930120

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	3 / 7
TPSA	112 Å²

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P280, P318, P319, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 21-Carboxy Dexamethasone?

The CAS Registry Number of 21-Carboxy Dexamethasone is 84449-15-0. It is also known as Dexamethasone Glyoxal Analog, (11beta,16alpha)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-oic acid, (11ss,16a)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxo-pregna-1,4-dien-21-oic acid.

What is the molecular formula and molecular weight of 21-Carboxy Dexamethasone?

21-Carboxy Dexamethasone has the molecular formula C22H27FO6 and a molecular weight of 406.4 g/mol.

What is 21-Carboxy Dexamethasone used for?

21-Carboxy Dexamethasone is supplied as a characterised reference material related to Dexamethasone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 21-Carboxy Dexamethasone can I order?

We supply 21-Carboxy Dexamethasone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 21-Carboxy Dexamethasone?

Yes. Every lot of 21-Carboxy Dexamethasone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 21-Carboxy Dexamethasone be shipped internationally?

Yes. 21-Carboxy Dexamethasone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.