Dexamethasone EP Impurity I

Name: Dexamethasone EP Impurity I
Brand: Vaqora Chemicals
SKU: VQ-022343

About Dexamethasone EP Impurity I

Dexamethasone EP Impurity I is a pharmacopeial impurity of Dexamethasone carrying the CAS registry number 14622-47-0. With the molecular formula C22H28O5, it has a molar mass of 372.5 g/mol. It is also known as Dexamethasone - Impurity I or Dexamethasone Impurity I.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Dexamethasone, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Dexamethasone EP Impurity I in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Dexamethasone

View every impurity, metabolite and intermediate we list for Dexamethasone.

Dexamethasone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Dexamethasone EP Impurity I
Catalogue No.	VQ-022343
CAS Number	14622-47-0
IUPAC name	(1R,2S,10S,11S,13R,14R,15S,17R)-14-hydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyl-18-oxapentacyclo[8.8.0.01,17.02,7.011,15]octadeca-3,6-dien-5-one
Molecular formula	C₂₂H₂₈O₅
Molecular weight	372.5 g/mol
Exact mass	372.1937
Grade	Reference Standard
HSN code	38229090
InChIKey	GBDXNHBVYAMODG-HGBIFODKSA-N
SMILES	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@@]35[C@H](O5)C[C@@]2([C@]1(C(=O)CO)O)C)C
PubChem CID	7067877

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	2 / 5
TPSA	87.1 Å²
Synonyms	(11a,16a)-9,11-Epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione, Dexamethasone - Impurity I, (11alpha,16alpha)-9,11-Epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione, 9alpha,11alpha-Epoxy-17,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione, Pregna-1,4-diene-3,20-dione, 9,11-epoxy-17,21-dihydroxy-16-methyl-, (11alpha,16alpha)-, Dexamethasone Impurity I, Dexamethasone Impurity 1, (11, A,16, A)-9,11-Epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dexamethasone EP Impurity I?

The CAS Registry Number of Dexamethasone EP Impurity I is 14622-47-0. It is also known as (11a,16a)-9,11-Epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione, Dexamethasone - Impurity I, (11alpha,16alpha)-9,11-Epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione.

What is the molecular formula and molecular weight of Dexamethasone EP Impurity I?

Dexamethasone EP Impurity I has the molecular formula C22H28O5 and a molecular weight of 372.5 g/mol. Its IUPAC name is (1R,2S,10S,11S,13R,14R,15S,17R)-14-hydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyl-18-oxapentacyclo[8.8.0.01,17.02,7.011,15]octadeca-3,6-dien-5-one.

What is Dexamethasone EP Impurity I used for?

Dexamethasone EP Impurity I is supplied as a characterised reference material related to Dexamethasone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dexamethasone EP Impurity I can I order?

We supply Dexamethasone EP Impurity I in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dexamethasone EP Impurity I?

Yes. Every lot of Dexamethasone EP Impurity I is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dexamethasone EP Impurity I be shipped internationally?

Yes. We export Dexamethasone EP Impurity I worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.