21-Chloro Dexamethasone

Name: 21-Chloro Dexamethasone
Brand: Vaqora Chemicals
SKU: VQ-036655

About 21-Chloro Dexamethasone

Vaqora Chemicals supplies 21-Chloro Dexamethasone, an impurity of Dexamethasone registered under CAS number 61319-46-8. With the molecular formula C22H28ClFO4, it has a molar mass of 410.9 g/mol. It is also known as 16-epi-Clobetasol.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Dexamethasone impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Dexamethasone

View every impurity, metabolite and intermediate we list for Dexamethasone.

Dexamethasone impurities

Specifications & identifiers

Chemical identifiers
Product name	21-Chloro Dexamethasone
Catalogue No.	VQ-036655
CAS Number	61319-46-8
IUPAC name	(8S,9R,10S,11S,13S,14S,16R,17R)-17-(2-chloroacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
Molecular formula	C₂₂H₂₈ClFO₄
Molecular weight	410.9 g/mol
Exact mass	410.166
Grade	Reference Standard
HSN code	38229090
InChIKey	FCSHDIVRCWTZOX-CXSFZGCWSA-N
SMILES	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CCl)O)C)O)F)C
PubChem CID	12966679

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	2 / 5
TPSA	74.6 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 21-Chloro Dexamethasone?

The CAS Registry Number of 21-Chloro Dexamethasone is 61319-46-8. It is also known as 16-epi-Clobetasol, 21-Chloro-9-fluoro-11beta,17-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione.

What is the molecular formula and molecular weight of 21-Chloro Dexamethasone?

21-Chloro Dexamethasone has the molecular formula C22H28ClFO4 and a molecular weight of 410.9 g/mol. Its IUPAC name is (8S,9R,10S,11S,13S,14S,16R,17R)-17-(2-chloroacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one.

What is 21-Chloro Dexamethasone used for?

21-Chloro Dexamethasone is supplied as a characterised reference material related to Dexamethasone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 21-Chloro Dexamethasone can I order?

We supply 21-Chloro Dexamethasone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 21-Chloro Dexamethasone?

Yes. Every lot of 21-Chloro Dexamethasone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 21-Chloro Dexamethasone be shipped internationally?

Yes. We export 21-Chloro Dexamethasone worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.