21-Chloro Hydrocortisone

Name: 21-Chloro Hydrocortisone
Brand: Vaqora Chemicals
SKU: VQ-022812

About 21-Chloro Hydrocortisone

21-Chloro Hydrocortisone (CAS 75868-48-3) is an impurity of Hydrocortisone offered by Vaqora Chemicals. With the molecular formula C21H27ClO3, it has a molar mass of 362.9 g/mol. Alternative names: 21-Desacetoxy-21-Chloro Anecortave.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Hydrocortisone impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer 21-Chloro Hydrocortisone in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. A Safety Data Sheet (SDS) and technical specifications are available on request.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Hydrocortisone

View every impurity, metabolite and intermediate we list for Hydrocortisone.

Hydrocortisone impurities

Specifications & identifiers

Chemical identifiers
Product name	21-Chloro Hydrocortisone
Catalogue No.	VQ-022812
CAS Number	75868-48-3
IUPAC name	(8S,10S,13S,14S,17R)-17-(2-chloroacetyl)-17-hydroxy-10,13-dimethyl-2,6,7,8,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one
Molecular formula	C₂₁H₂₇ClO₃
Molecular weight	362.9 g/mol
Exact mass	362.1649
Grade	Reference Standard
HSN code	38229090
InChIKey	YFXBALFUWXVJMK-ONKRVSLGSA-N
SMILES	C[C@]12CCC(=O)C=C1CC[C@@H]3C2=CC[C@]4([C@H]3CC[C@@]4(C(=O)CCl)O)C
PubChem CID	13037654

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	1 / 3
TPSA	54.4 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 21-Chloro Hydrocortisone?

The CAS Registry Number of 21-Chloro Hydrocortisone is 75868-48-3. It is also known as 21-Desacetoxy-21-Chloro Anecortave, 21-chloro-17-hydroxy-pregna-4,9(11)-diene-3,20-dione, 21-Chloro-17alpha-hydroxypregna-4,9(11)-diene-3,20-dione.

What is the molecular formula and molecular weight of 21-Chloro Hydrocortisone?

21-Chloro Hydrocortisone has the molecular formula C21H27ClO3 and a molecular weight of 362.9 g/mol. Its IUPAC name is (8S,10S,13S,14S,17R)-17-(2-chloroacetyl)-17-hydroxy-10,13-dimethyl-2,6,7,8,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one.

What is 21-Chloro Hydrocortisone used for?

21-Chloro Hydrocortisone is supplied as a characterised reference material related to Hydrocortisone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 21-Chloro Hydrocortisone can I order?

We supply 21-Chloro Hydrocortisone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 21-Chloro Hydrocortisone?

Yes. Every lot of 21-Chloro Hydrocortisone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 21-Chloro Hydrocortisone be shipped internationally?

Yes. We export 21-Chloro Hydrocortisone worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.