Hydrocortisone 21-Butyrate

Name: Hydrocortisone 21-Butyrate
Brand: Vaqora Chemicals
SKU: VQ-022808

About Hydrocortisone 21-Butyrate

Hydrocortisone 21-Butyrate is an impurity of Hydrocortisone carrying the CAS registry number 6677-99-2. The compound has the formula C25H36O6, corresponding to a molecular weight of 432.5 g/mol. Common synonyms include Isdinium and Stero To.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Hydrocortisone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Hydrocortisone 21-Butyrate in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Hydrocortisone

View every impurity, metabolite and intermediate we list for Hydrocortisone.

Hydrocortisone impurities

Specifications & identifiers

Chemical identifiers
Product name	Hydrocortisone 21-Butyrate
Catalogue No.	VQ-022808
CAS Number	6677-99-2
IUPAC name	[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] butanoate
Molecular formula	C₂₅H₃₆O₆
Molecular weight	432.5 g/mol
Exact mass	432.2512
Grade	Reference Standard
HSN code	38229090
InChIKey	YZNQMPPBWQTLFJ-TUFAYURCSA-N
SMILES	CCCC(=O)OCC(=O)[C@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)O)C)O
PubChem CID	10365526

Physical properties
Physical form	Solid
LogP (XLogP3)	3.1
H-bond donors / acceptors	2 / 6
TPSA	101 Å²
Synonyms	Isdinium, Stero To, 11beta,17,21-Trihydroxypregn-4-ene-3,20-dione 21-butyrate, HB(sub 21), hydrocortison-21-butyrat, Pregn-4-en-3,20-dione, 11,17-dihydroxy-21-(1-oxobutoxy)-, (11-beta)-, 11beta,17-Dihydroxy-3,20-dioxopregn-4-en-21-yl butanoate, (11b)-11,17-Dihydroxy-21-(1-oxobutoxy)pregn-4-ene-3,20-dione

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H341Suspected of causing genetic defects

Precautionary statements: P203, P264, P270, P280, P301 + P317, P318, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Hydrocortisone 21-Butyrate?

The CAS Registry Number of Hydrocortisone 21-Butyrate is 6677-99-2. It is also known as Isdinium, Stero To, 11beta,17,21-Trihydroxypregn-4-ene-3,20-dione 21-butyrate.

What is the molecular formula and molecular weight of Hydrocortisone 21-Butyrate?

Hydrocortisone 21-Butyrate has the molecular formula C25H36O6 and a molecular weight of 432.5 g/mol.

What is Hydrocortisone 21-Butyrate used for?

Hydrocortisone 21-Butyrate is supplied as a characterised reference material related to Hydrocortisone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Hydrocortisone 21-Butyrate can I order?

We supply Hydrocortisone 21-Butyrate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Hydrocortisone 21-Butyrate?

Yes. Every lot of Hydrocortisone 21-Butyrate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Hydrocortisone 21-Butyrate be shipped internationally?

Yes. Hydrocortisone 21-Butyrate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.