21-Dehydrocortisone

Name: 21-Dehydrocortisone
Brand: Vaqora Chemicals
SKU: VQ-031098

About 21-Dehydrocortisone

21-Dehydrocortisone is an impurity of Hydrocortisone carrying the CAS registry number 16574-04-2. Formula C21H26O5, molecular weight 358.4 g/mol. Alternative names: 17-hydroxy-3,11,20-trioxopregn-4-en-21-al and Pregn-4-en-21-al,11,20-trioxo-.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Hydrocortisone, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 21-Dehydrocortisone is dispatched with a Certificate of Analysis (COA) to destinations worldwide. SDS and detailed specification sheets can be requested with your quotation.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Hydrocortisone

View every impurity, metabolite and intermediate we list for Hydrocortisone.

Hydrocortisone impurities

Specifications & identifiers

Chemical identifiers
Product name	21-Dehydrocortisone
Catalogue No.	VQ-031098
CAS Number	16574-04-2
IUPAC name	2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoacetaldehyde
Molecular formula	C₂₁H₂₆O₅
Molecular weight	358.4 g/mol
Exact mass	358.178
Grade	Reference Standard
HSN code	38229090
InChIKey	DJLICGGNASJAQR-ZPOLXVRWSA-N
SMILES	C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2C(=O)C[C@]4([C@H]3CC[C@@]4(C(=O)C=O)O)C
PubChem CID	331383

Physical properties
Physical form	Solid
LogP (XLogP3)	1.8
H-bond donors / acceptors	1 / 5
TPSA	88.5 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 21-Dehydrocortisone?

The CAS Registry Number of 21-Dehydrocortisone is 16574-04-2. It is also known as 17-hydroxy-3,11,20-trioxopregn-4-en-21-al, Pregn-4-en-21-al,11,20-trioxo-, 4-pregnen-17alpha-ol-3,11,20-trione-21-al.

What is the molecular formula and molecular weight of 21-Dehydrocortisone?

21-Dehydrocortisone has the molecular formula C21H26O5 and a molecular weight of 358.4 g/mol. Its IUPAC name is 2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoacetaldehyde.

What is 21-Dehydrocortisone used for?

21-Dehydrocortisone is supplied as a characterised reference material related to Hydrocortisone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 21-Dehydrocortisone can I order?

We supply 21-Dehydrocortisone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 21-Dehydrocortisone?

Yes. Every lot of 21-Dehydrocortisone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 21-Dehydrocortisone be shipped internationally?

Yes. We export 21-Dehydrocortisone worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.