2,3-Dehydrosilybin B

Name: 2,3-Dehydrosilybin B
Brand: Vaqora Chemicals
SKU: VQ-042178

About 2,3-Dehydrosilybin B

2,3-Dehydrosilybin B is an impurity of Silymarin carrying the CAS registry number 142796-24-5. Its molecular formula is C25H20O10 and its molecular weight is 480.4 g/mol.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Silymarin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 2,3-Dehydrosilybin B is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Silymarin

View every impurity, metabolite and intermediate we list for Silymarin.

Silymarin impurities

Specifications & identifiers

Chemical identifiers
Product name	2,3-Dehydrosilybin B
Catalogue No.	VQ-042178
CAS Number	142796-24-5
IUPAC name	3,5,7-trihydroxy-2-[(2S,3S)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]chromen-4-one
Molecular formula	C₂₅H₂₀O₁₀
Molecular weight	480.4 g/mol
Exact mass	480.1056
Grade	Reference Standard
HSN code	38229090
InChIKey	BVKQRAYKLBRNIK-RDPSFJRHSA-N
SMILES	COC1=C(C=CC(=C1)[C@H]2[C@@H](OC3=C(O2)C=C(C=C3)C4=C(C(=O)C5=C(C=C(C=C5O4)O)O)O)CO)O
PubChem CID	12051803

Physical properties
Physical form	Solid
LogP (XLogP3)	3.1
H-bond donors / acceptors	5 / 10
TPSA	155 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2,3-Dehydrosilybin B?

The CAS Registry Number of 2,3-Dehydrosilybin B is 142796-24-5.

What is the molecular formula and molecular weight of 2,3-Dehydrosilybin B?

2,3-Dehydrosilybin B has the molecular formula C25H20O10 and a molecular weight of 480.4 g/mol. Its IUPAC name is 3,5,7-trihydroxy-2-[(2S,3S)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]chromen-4-one.

What is 2,3-Dehydrosilybin B used for?

2,3-Dehydrosilybin B is supplied as a characterised reference material related to Silymarin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2,3-Dehydrosilybin B can I order?

We supply 2,3-Dehydrosilybin B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2,3-Dehydrosilybin B?

Yes. Every lot of 2,3-Dehydrosilybin B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2,3-Dehydrosilybin B be shipped internationally?

Yes. 2,3-Dehydrosilybin B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.