Silybin A,B (mixture)

Name: Silybin A,B (mixture)
Brand: Vaqora Chemicals
SKU: VQ-042177

About Silybin A,B (mixture)

Silybin A,B (mixture) (CAS 802918-57-6) is a process intermediate or related compound of Silymarin offered by Vaqora Chemicals. The compound has the formula C25H22O10, corresponding to a molecular weight of 482.4 g/mol. It is also known as Silybin,mixture of A and B or Silybin.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

It is a process intermediate or related compound in the synthesis of Silymarin, useful for route development, impurity fate-and-purge studies and analytical method development. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Silybin A,B (mixture) is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development
Fine chemical synthesis

Industries

Related to Silymarin

View every impurity, metabolite and intermediate we list for Silymarin.

Silymarin impurities

Specifications & identifiers

Chemical identifiers
Product name	Silybin A,B (mixture)
Catalogue No.	VQ-042177
CAS Number	802918-57-6
IUPAC name	(2R,3R)-3,5,7-trihydroxy-2-[3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydrochromen-4-one
Molecular formula	C₂₅H₂₂O₁₀
Molecular weight	482.4 g/mol
Exact mass	482.1213
InChIKey	SEBFKMXJBCUCAI-DBMPWETRSA-N
SMILES	COC1=C(C=CC(=C1)C2C(OC3=C(O2)C=C(C=C3)[C@@H]4[C@H](C(=O)C5=C(C=C(C=C5O4)O)O)O)CO)O
PubChem CID	3086637

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	5 / 10
TPSA	155 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Silybin A,B (mixture)?

The CAS Registry Number of Silybin A,B (mixture) is 802918-57-6. It is also known as Silybin,mixture of A and B, Silybin, Silibin.

What is the molecular formula and molecular weight of Silybin A,B (mixture)?

Silybin A,B (mixture) has the molecular formula C25H22O10 and a molecular weight of 482.4 g/mol. Its IUPAC name is (2R,3R)-3,5,7-trihydroxy-2-[3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydrochromen-4-one.

What is Silybin A,B (mixture) used for?

Silybin A,B (mixture) is supplied as a characterised reference material related to Silymarin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Silybin A,B (mixture) can I order?

We supply Silybin A,B (mixture), in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Silybin A,B (mixture)?

Yes. Every lot of Silybin A,B (mixture) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Silybin A,B (mixture) be shipped internationally?

Yes. Silybin A,B (mixture) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.