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VAQORACHEMICALS

2,4-Difluorobenzyl Chloride

Synonyms: 2,4-Difluorobenzyl Chloride · 1-(chloromethyl)-2,4-difluoro-benzene · 2,4-difluorobenzylchloride · Benzene, 1-(chloromethyl)-2,4-difluoro-

CAS No.452-07-3
FormulaC7H5ClF2
Mol. weight162.56
Catalogue No.VQ-012886
PurityReference Standard
HSN—

2,4-Difluorobenzyl Chloride (CAS 452-07-3) – Relugolix intermediate. C7H5ClF2, MW 162.56. Get a quote from Vaqora Chemicals, COA included, shipped worldwide.

Pack sizesPrice on quotation · bulk available
10 mg
25 mg
50 mg
Bulk / custom pack · kg to MT
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Batch COA with every lot
16-section GHS SDS
Export to 120+ countries
DG-compliant packing

About 2,4-Difluorobenzyl Chloride

2,4-Difluorobenzyl Chloride is a process intermediate or related compound of Relugolix carrying the CAS registry number 452-07-3. Formula C7H5ClF2, molecular weight 162.56 g/mol. The IUPAC name is 1-(chloromethyl)-2,4-difluorobenzene. It is also known as 1-(chloromethyl)-2,4-difluoro-benzene or 2,4-difluorobenzylchloride.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

It is a process intermediate or related compound in the synthesis of Relugolix, useful for route development, impurity fate-and-purge studies and analytical method development. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 2,4-Difluorobenzyl Chloride in 10 mg, 25 mg and 50 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. This item is currently in stock for prompt dispatch.

Typical applications

  • API route development
  • Impurity fate & purge studies
  • Analytical method development

Industries

Related to Relugolix

View every impurity, metabolite and intermediate we list for Relugolix.

Relugolix impurities

Specifications & identifiers

Chemical identifiers
Product name2,4-Difluorobenzyl Chloride
Catalogue No.VQ-012886
CAS Number452-07-3
IUPAC name1-(chloromethyl)-2,4-difluorobenzene
Molecular formulaC7H5ClF2
Molecular weight162.56 g/mol
Exact mass162.0048
GradeReference Standard
InChIKeyXPGHWBDZNQUUQD-UHFFFAOYSA-N
SMILESC1=CC(=C(C=C1F)F)CCl
PubChem CID2736948
Physical properties
Physical formSolid
LogP (XLogP3)2.8
H-bond donors / acceptors0 / 2
TPSA0 Ų
Synonyms2,4-Difluorobenzyl Chloride, 1-(chloromethyl)-2,4-difluoro-benzene, 2,4-difluorobenzylchloride, Benzene, 1-(chloromethyl)-2,4-difluoro-, alpha-Chloro-2,4-difluorotoluene, 2,4-difluoro-benzyl chloride

Safety & hazard information (GHS)

GHS05 Corrosive
Corrosive
GHS07 Harmful / irritant
Harmful / irritant

Signal word: Danger

Hazard statements

  • H290May be corrosive to metals
  • H302Harmful if swallowed
  • H314Causes severe skin burns and eye damage
  • H318Causes serious eye damage
  • H332Harmful if inhaled

Precautionary statements: P234, P260, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P301 + P330 + P331, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P317, P321, P330, P363, P390, P405, P406, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Frequently asked questions

What is the CAS number of 2,4-Difluorobenzyl Chloride?

The CAS Registry Number of 2,4-Difluorobenzyl Chloride is 452-07-3. It is also known as 2,4-Difluorobenzyl Chloride, 1-(chloromethyl)-2,4-difluoro-benzene, 2,4-difluorobenzylchloride.

What is the molecular formula and molecular weight of 2,4-Difluorobenzyl Chloride?

2,4-Difluorobenzyl Chloride has the molecular formula C7H5ClF2 and a molecular weight of 162.56 g/mol. Its IUPAC name is 1-(chloromethyl)-2,4-difluorobenzene.

What is 2,4-Difluorobenzyl Chloride used for?

2,4-Difluorobenzyl Chloride is supplied as a characterised reference material related to Relugolix. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2,4-Difluorobenzyl Chloride can I order?

We supply 2,4-Difluorobenzyl Chloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2,4-Difluorobenzyl Chloride?

Yes. Every lot of 2,4-Difluorobenzyl Chloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2,4-Difluorobenzyl Chloride be shipped internationally?

Yes. 2,4-Difluorobenzyl Chloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.

Enquire about 2,4-Difluorobenzyl Chloride

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Why buyers choose Vaqora

  • Batch-traceable lots with COA
  • R&D packs to multi-tonne supply
  • IATA / IMDG dangerous-goods packing
  • EXW, FOB, CIF, DAP Incoterms
  • Custom synthesis & sourcing
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