2,5-Difluorophenylacetic acid

Name: 2,5-Difluorophenylacetic acid
Brand: Vaqora Chemicals
SKU: VQ-027138

About 2,5-Difluorophenylacetic acid

Vaqora Chemicals supplies 2,5-Difluorophenylacetic acid, an impurity of Sitagliptin registered under CAS number 85068-27-5. The compound has the formula C8H6F2O2, corresponding to a molecular weight of 172.13 g/mol. Systematically, it is named 2-(2,5-difluorophenyl)acetic acid. Common synonyms include Benzeneacetic acid, 2,5-difluoro- and Benzeneacetic acid, 2,5-difluoro.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

This Sitagliptin impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer 2,5-Difluorophenylacetic acid in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sitagliptin

View every impurity, metabolite and intermediate we list for Sitagliptin.

Sitagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	2,5-Difluorophenylacetic acid
Catalogue No.	VQ-027138
CAS Number	85068-27-5
IUPAC name	2-(2,5-difluorophenyl)acetic acid
Molecular formula	C₈H₆F₂O₂
Molecular weight	172.13 g/mol
Exact mass	172.0336
Grade	Reference Standard
HSN code	38229090
InChIKey	FKCRTRYQHZHXES-UHFFFAOYSA-N
SMILES	C1=CC(=C(C=C1F)CC(=O)O)F
PubChem CID	522823

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	1 / 4
TPSA	37.3 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2,5-Difluorophenylacetic acid?

The CAS Registry Number of 2,5-Difluorophenylacetic acid is 85068-27-5. It is also known as Benzeneacetic acid, 2,5-difluoro-, Benzeneacetic acid, 2,5-difluoro.

What is the molecular formula and molecular weight of 2,5-Difluorophenylacetic acid?

2,5-Difluorophenylacetic acid has the molecular formula C8H6F2O2 and a molecular weight of 172.13 g/mol. Its IUPAC name is 2-(2,5-difluorophenyl)acetic acid.

What is 2,5-Difluorophenylacetic acid used for?

2,5-Difluorophenylacetic acid is supplied as a characterised reference material related to Sitagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2,5-Difluorophenylacetic acid can I order?

We supply 2,5-Difluorophenylacetic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2,5-Difluorophenylacetic acid?

Yes. Every lot of 2,5-Difluorophenylacetic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2,5-Difluorophenylacetic acid be shipped internationally?

Yes. 2,5-Difluorophenylacetic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.