25-Hydroxyvitamin D3

Name: 25-Hydroxyvitamin D3
Brand: Vaqora Chemicals
SKU: VQ-029585

About 25-Hydroxyvitamin D3

25-Hydroxyvitamin D3 is a metabolite or degradation product of Cholecalciferol carrying the CAS registry number 19356-17-3. The compound has the formula C27H44O2, corresponding to a molecular weight of 400.6 g/mol. It is also known as Calcifediol or 25-Hydroxy Cholecalciferol.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 5 hazard statements. Review the Safety Data Sheet before use.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Cholecalciferol, as well as in QC testing and ANDA/DMF documentation. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 25-Hydroxyvitamin D3 in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Cholecalciferol

View every impurity, metabolite and intermediate we list for Cholecalciferol.

Cholecalciferol impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	25-Hydroxyvitamin D3
Catalogue No.	VQ-029585
CAS Number	19356-17-3
IUPAC name	(1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol
Molecular formula	C₂₇H₄₄O₂
Molecular weight	400.6 g/mol
Exact mass	400.3341
Grade	Reference Standard
HSN code	38229090
InChIKey	JWUBBDSIWDLEOM-DTOXIADCSA-N
SMILES	C[C@H](CCCC(C)(C)O)[C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C/3\C[C@H](CCC3=C)O)C
PubChem CID	5283731

Physical properties
Physical form	Solid
LogP (XLogP3)	6.2
H-bond donors / acceptors	2 / 2
TPSA	40.5 Å²
Synonyms	Calcifediol, 25-Hydroxy Cholecalciferol, Calcidiol, Calcifediol anhydrous, Didrogyl, 5,6-cis-25-Hydroxyvitamin D3, Cholecalciferol, 25-hydroxy-, 25-Hydroxycholescalciferol, 9,10-Secocholesta-5,7,10(19)-triene-3beta,25-diol, 25-Hydroxycholecalciferol monohydrate, 25(OH)D3, 5,6-trans-25-Hydroxycholescalciferol

Safety & hazard information (GHS)

Toxic

Health hazard

Signal word: Danger

Hazard statements

H301+H311Toxic if swallowed or in contact with skin
H301Toxic if swallowed
H311Toxic in contact with skin
H330Fatal if inhaled
H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements: P260, P262, P264, P270, P271, P280, P284, P301 + P316, P302 + P352, P304 + P340, P316, P319, P320, P321, P330, P361 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 25-Hydroxyvitamin D3?

The CAS Registry Number of 25-Hydroxyvitamin D3 is 19356-17-3. It is also known as Calcifediol, 25-Hydroxy Cholecalciferol, Calcidiol.

What is the molecular formula and molecular weight of 25-Hydroxyvitamin D3?

25-Hydroxyvitamin D3 has the molecular formula C27H44O2 and a molecular weight of 400.6 g/mol.

What is 25-Hydroxyvitamin D3 used for?

25-Hydroxyvitamin D3 is supplied as a characterised reference material related to Cholecalciferol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 25-Hydroxyvitamin D3 can I order?

We supply 25-Hydroxyvitamin D3 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 25-Hydroxyvitamin D3?

Yes. Every lot of 25-Hydroxyvitamin D3 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 25-Hydroxyvitamin D3 be shipped internationally?

Yes. 25-Hydroxyvitamin D3 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.