3-(3,4-Difluorophenyl)acryloyl chloride

Name: 3-(3,4-Difluorophenyl)acryloyl chloride
Brand: Vaqora Chemicals
SKU: VQ-040009

About 3-(3,4-Difluorophenyl)acryloyl chloride

3-(3,4-Difluorophenyl)acryloyl chloride is an impurity of Ticagrelor carrying the CAS registry number 1043546-64-0. The compound has the formula C9H5ClF2O, corresponding to a molecular weight of 202.58 g/mol. Its systematic (IUPAC) name is (E)-3-(3,4-difluorophenyl)prop-2-enoyl chloride. Alternative names: 3,4-difluorocinnamoyl chloride and (E)-3-(3,4-difluorophenyl)acryloyl chloride.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Ticagrelor to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ticagrelor

View every impurity, metabolite and intermediate we list for Ticagrelor.

Ticagrelor impurities

Specifications & identifiers

Chemical identifiers
Product name	3-(3,4-Difluorophenyl)acryloyl chloride
Catalogue No.	VQ-040009
CAS Number	1043546-64-0
IUPAC name	(E)-3-(3,4-difluorophenyl)prop-2-enoyl chloride
Molecular formula	C₉H₅ClF₂O
Molecular weight	202.58 g/mol
Exact mass	201.9997
Grade	Reference Standard
HSN code	38229090
InChIKey	HLVDWMSYSIMRNI-DUXPYHPUSA-N
SMILES	C1=CC(=C(C=C1/C=C/C(=O)Cl)F)F
PubChem CID	9920680

Physical properties
Physical form	Solid
LogP (XLogP3)	3.1
H-bond donors / acceptors	0 / 3
TPSA	17.1 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-(3,4-Difluorophenyl)acryloyl chloride?

The CAS Registry Number of 3-(3,4-Difluorophenyl)acryloyl chloride is 1043546-64-0. It is also known as (2E)-3-(3,4-Difluorophenyl)-2-propenoyl chloride, 3,4-difluorocinnamoyl chloride, (E)-3-(3,4-difluorophenyl)acryloyl chloride.

What is the molecular formula and molecular weight of 3-(3,4-Difluorophenyl)acryloyl chloride?

3-(3,4-Difluorophenyl)acryloyl chloride has the molecular formula C9H5ClF2O and a molecular weight of 202.58 g/mol. Its IUPAC name is (E)-3-(3,4-difluorophenyl)prop-2-enoyl chloride.

What is 3-(3,4-Difluorophenyl)acryloyl chloride used for?

3-(3,4-Difluorophenyl)acryloyl chloride is supplied as a characterised reference material related to Ticagrelor. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-(3,4-Difluorophenyl)acryloyl chloride can I order?

We supply 3-(3,4-Difluorophenyl)acryloyl chloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-(3,4-Difluorophenyl)acryloyl chloride?

Yes. Every lot of 3-(3,4-Difluorophenyl)acryloyl chloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-(3,4-Difluorophenyl)acryloyl chloride be shipped internationally?

Yes. We export 3-(3,4-Difluorophenyl)acryloyl chloride worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.