Impurity reference standards
Ticagrelor impurities & reference standards
Characterised Ticagrelor impurities, degradation products and related compounds for analytical method development, validation, QC release and regulatory filings.
143reference materials
3nitrosamine impurities
1isotope-labelled
COAHPLC · NMR · MS on request
Parent API: Ticagrelor
274693-27-5 · C23H28F2N6O4S
(1R,2R)-2-(3,4-Difluorophenyl)-cyclopropanecarboxylic Acid
- CAS
- 220352-36-3
- Formula
- C10H8F2O2
- MW
- 198.17 g/mol
VQ-034232
(1R,2R)-2-(3,4-Difluorophenyl)-N-hydroxycyclopropane-1-carboxamide
- CAS
- 1353964-60-9
- Formula
- C10H9F2NO2
- MW
- 213.18 g/mol
VQ-034255
(1R,2R)-2-(3,4-Difluorophenyl)cyclopropane-1-carbonyl Chloride
- CAS
- 376608-70-7
- Formula
- C10H7ClF2O
- MW
- 216.61 g/mol
VQ-044301
(1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarbonyl azide
- CAS
- 378236-67-0
- Formula
- C10H7F2N3O
- MW
- 223.18 g/mol
VQ-042515
(1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxamide
- CAS
- 1006376-62-0
- Formula
- C10H9F2NO
- MW
- 197.18 g/mol
VQ-023894
(1R,2R)-2-(4-Fluorophenyl)cyclopropanamine hydrochloride
- CAS
- 1450903-24-8
- Formula
- C9H11ClFN
- MW
- 187.64 g/mol
VQ-042517
(1R,2S)-2-(2,3-Difluorophenyl)cyclopropan-1-amine
- CAS
- 1427524-53-5
- Formula
- C9H9F2N
- MW
- 169.17 g/mol
VQ-034237
(1R,2S)-2-(3-Fluorophenyl)cyclopropan-1-amine hydrochloride
- CAS
- 1643378-58-8
- Formula
- C9H11ClFN
- MW
- 187.64 g/mol
VQ-042540
(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanecarboxylic acid
- CAS
- 1414348-38-1
- Formula
- C10H8F2O2
- MW
- 198.17 g/mol
VQ-034250
(1R,2S)-Rel-2-(3,4-Difluorophenyl) cyclopropanamine hydrochloride
- CAS
- 1156491-10-9
- Formula
- C9H10ClF2N
- MW
- 205.63 g/mol
VQ-034229
![(1S,2R,3S,4R)-4-(7-(((1S,2S)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)cyclopentane-1,2,3-triol chemical structure](/media/structures/XYLIQTKEYHWYGG-ZLMUUKSWSA-N.svg)
(1S,2R,3S,4R)-4-(7-(((1S,2S)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)cyclopentane-1,2,3-triol
- CAS
- 2245167-79-5
- Formula
- C21H24F2N6O3S
- MW
- 478.5 g/mol
VQ-044097
(1S,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylic acid
- CAS
- 2051515-36-5
- Formula
- C10H8F2O2
- MW
- 198.17 g/mol
VQ-034249
(1S,2R)-2-(4-Fluorophenyl)cyclopropan-1-amine hydrochloride
- CAS
- 1990505-73-1
- Formula
- C9H11ClFN
- MW
- 187.64 g/mol
VQ-042537
(1S,2S,3R,5S)-3-(5-Amino-6-chloro-2-(propylthio)pyrimidin-4-ylamino)-5-(2-hydroxyethoxy)cyclopentane
- CAS
- 1402150-32-6
- Formula
- C14H23ClN4O4S
- MW
- 378.9 g/mol
VQ-034225
![(1S,2S,3R,5S)-3-(7-(((1R,2R)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol chemical structure](/media/structures/OEKWJQXRCDYSHL-AVDPAMPWSA-N.svg)
(1S,2S,3R,5S)-3-(7-(((1R,2R)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
- CAS
- 2056269-94-2
- Formula
- C23H28F2N6O4S
- MW
- 522.6 g/mol
VQ-028362
![(1S,2S,3R,5S)-3-(7-(((1S,2R)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol chemical structure](/media/structures/OEKWJQXRCDYSHL-KCODXIBCSA-N.svg)
(1S,2S,3R,5S)-3-(7-(((1S,2R)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
- CAS
- 2096989-56-7
- Formula
- C23H28F2N6O4S
- MW
- 522.6 g/mol
VQ-034223
![(1S,2S,3R,5S)-3-(7-(((1S,2S)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol chemical structure](/media/structures/OEKWJQXRCDYSHL-OVGQVHOSSA-N.svg)
(1S,2S,3R,5S)-3-(7-(((1S,2S)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
- CAS
- 2435586-40-4
- Formula
- C23H28F2N6O4S
- MW
- 522.6 g/mol
VQ-034242
![(1S,2S,3R,5S)-3-(7-Hydroxy-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol chemical structure](/media/structures/YMQPMTYKFZPQGL-YKDSUIRESA-N.svg)
(1S,2S,3R,5S)-3-(7-Hydroxy-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
- CAS
- 1445580-43-7
- Formula
- C14H21N5O5S
- MW
- 371.41 g/mol
VQ-028360
![(1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(2,3-Difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol chemical structure](/media/structures/LRERWNWIRJOJAN-QXZAJCAHSA-N.svg)
(1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(2,3-Difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol
- CAS
- 1643378-48-6
- Formula
- C23H28F2N6O4S
- MW
- 522.6 g/mol
VQ-028365
![(1S,2S,3R,5S)-3-[7-Chloro-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol chemical structure](/media/structures/OPHFHASJVWECNO-MKHNBGRSSA-N.svg)
(1S,2S,3R,5S)-3-[7-Chloro-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol
- CAS
- 1354945-69-9
- Formula
- C14H20ClN5O4S
- MW
- 389.9 g/mol
VQ-043328
(1S,2S,3R,5S)-3-Amino-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
- CAS
- 1444301-60-3
- Formula
- C7H15NO4
- MW
- 177.2 g/mol
VQ-034257
(1S,2S)-2-(3,4-Difluorophenyl)-cyclopropanamine hydrochloride
- CAS
- 3094994-75-6
- Formula
- C9H10ClF2N
- MW
- 205.63 g/mol
VQ-042542
(1S,2S)-2-(3,4-Difluorophenyl)cyclopropanecarboxylic acid
- CAS
- 1459720-31-0
- Formula
- C10H8F2O2
- MW
- 198.17 g/mol
VQ-044683
![(3AR,4R,6R,6aS)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-ol](/media/pack/3ar4r6r6as-6-amino-22-dimethyltetrahydro-4h-cyclopentad13dioxol-4-ol.svg?v=3)
(3AR,4R,6R,6aS)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-ol
- CAS
- 151527-83-2
- Formula
- C8H15NO3
- MW
- 173.21 g/mol
VQ-028379
![(3AR,4R,6S,6aS)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-ol chemical structure](/media/structures/AXPYGRDXRLICKY-BNHYGAARSA-N.svg)
(3AR,4R,6S,6aS)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-ol
- CAS
- 2715109-35-4
- Formula
- C8H15NO3
- MW
- 173.21 g/mol
VQ-028380
![(3AR,4S,6S,6aS)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-ol chemical structure](/media/structures/AXPYGRDXRLICKY-ZTYPAOSTSA-N.svg)
(3AR,4S,6S,6aS)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-ol
- CAS
- 2376278-80-5
- Formula
- C8H15NO3
- MW
- 173.21 g/mol
VQ-028378
(3AS,4R,6S,6aR)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol
- CAS
- 592533-90-9
- Formula
- C8H15NO3
- MW
- 173.21 g/mol
VQ-034236
![(3AS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole chemical structure](/media/structures/AAEYGFITCYWQDV-WCTZXXKLSA-N.svg)
(3AS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole
- CAS
- 38838-06-1
- Formula
- C9H15IO4
- MW
- 314.12 g/mol
VQ-042518
(4R,5R)-2,2-Dimethyl-5-vinyl-1,3-dioxolane-4-carbaldehyde
- CAS
- 155934-55-7
- Formula
- C8H12O3
- MW
- 156.18 g/mol
VQ-034256
![(E)-3-(3,4-Difluorophenyl)-1-((3aS,6R,7aR)-8,8-dimethyl-2,2-dioxidohexahydro-1H-3a,6-methanobenzo[c]isothiazol-1-yl)prop-2-en-1-one chemical structure](/media/structures/RSZFNQMNZSXXIE-NALRDDBRSA-N.svg)
(E)-3-(3,4-Difluorophenyl)-1-((3aS,6R,7aR)-8,8-dimethyl-2,2-dioxidohexahydro-1H-3a,6-methanobenzo[c]isothiazol-1-yl)prop-2-en-1-one
- CAS
- 220352-29-4
- Formula
- C19H21F2NO3S
- MW
- 381.4 g/mol
VQ-034239
(Z)-N-Benzyl-1-((4S,5R)-2,2-dimethyl-5-vinyl-1,3-dioxolan-4-yl)methanimine oxide
- CAS
- 345898-95-5
- Formula
- C15H19NO3
- MW
- 261.3 g/mol
VQ-044705
![2-(((3AR,4R,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol chemical structure](/media/structures/WNYYMPICYAOQAE-LURQLKTLSA-N.svg)
2-(((3AR,4R,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol
- CAS
- 2376278-67-8
- Formula
- C10H19NO4
- MW
- 217.26 g/mol
VQ-034245
![2-(((3AR,4S,6R,6aS)-6-(7-Amino-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol chemical structure](/media/structures/OVLZXEDRPYLHFJ-RSLMWUCJSA-N.svg)
2-(((3AR,4S,6R,6aS)-6-(7-Amino-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol
- CAS
- 1858267-99-8
- Formula
- C17H26N6O4S
- MW
- 410.5 g/mol
VQ-028381
![2-(((3AR,4S,6S,6aS)-6-Amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol chemical structure](/media/structures/WNYYMPICYAOQAE-XSPKLOCKSA-N.svg)
2-(((3AR,4S,6S,6aS)-6-Amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol
- CAS
- 2376278-69-0
- Formula
- C10H19NO4
- MW
- 217.26 g/mol
VQ-028377
![2-(((3AS,4R,6S,6aR)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol (2S,3S)-2,3-dihydroxysuccinate chemical structure](/media/structures/XEYNXCGNMKWIDO-NGFGLYMVSA-N.svg)
2-(((3AS,4R,6S,6aR)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol (2S,3S)-2,3-dihydroxysuccinate
- CAS
- 2376278-72-5
- Formula
- C14H25NO10
- MW
- 367.35 g/mol
VQ-034235
![2-(((3AS,4S,6R,6aR)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol chemical structure](/media/structures/WNYYMPICYAOQAE-XAVMHZPKSA-N.svg)
2-(((3AS,4S,6R,6aR)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol
- CAS
- 2165799-36-8
- Formula
- C10H19NO4
- MW
- 217.26 g/mol
VQ-034248
4-Chloro-6-methoxy-2-(propylthio)-5-pyrimidinamine
- CAS
- 1431867-40-1
- Formula
- C8H12ClN3OS
- MW
- 233.72 g/mol
VQ-042514
4,6-Dichloro-2-(propylsulfinyl)pyrimidin-5-amine
- CAS
- 1823431-32-8
- Formula
- C7H9Cl2N3OS
- MW
- 254.14 g/mol
VQ-042513
FAQs — Ticagrelor impurities
Which Ticagrelor impurities do you supply?
We list 143 Ticagrelor-related reference materials, including process impurities, degradation products, nitrosamine impurities, stable-isotope-labelled standards and related compounds. Each is supplied with a COA, and characterisation data (HPLC, 1H-NMR, MS, IR) can be provided on request.
What are Ticagrelor impurity standards used for?
They are used for analytical method development and validation, impurity identification and quantification, forced-degradation and stability studies, and to support ANDA, DMF and other regulatory submissions under ICH Q3A/Q3B (and ICH M7 for mutagenic impurities).
Can you synthesise a Ticagrelor impurity that is not listed?
Yes. Our custom synthesis service can prepare and characterise unlisted impurities, metabolites and labelled analogues from milligram to gram scale. Share the structure or name and required quantity for a quotation.
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