3, 4-Dimethoxybenzyl chloride

Name: 3, 4-Dimethoxybenzyl chloride
Brand: Vaqora Chemicals
SKU: VQ-039028

About 3, 4-Dimethoxybenzyl chloride

3, 4-Dimethoxybenzyl chloride (CAS 7306-46-9) is an impurity of Verapamil offered by Vaqora Chemicals. With the molecular formula C9H11ClO2, it has a molar mass of 186.63 g/mol. Its systematic (IUPAC) name is 4-(chloromethyl)-1,2-dimethoxybenzene. Common synonyms include Veratryl chloride and Benzene, 4-(chloromethyl)-1,2-dimethoxy-.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 4 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Verapamil, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Verapamil

View every impurity, metabolite and intermediate we list for Verapamil.

Verapamil impurities

Specifications & identifiers

Chemical identifiers
Product name	3, 4-Dimethoxybenzyl chloride
Catalogue No.	VQ-039028
CAS Number	7306-46-9
IUPAC name	4-(chloromethyl)-1,2-dimethoxybenzene
Molecular formula	C₉H₁₁ClO₂
Molecular weight	186.63 g/mol
Exact mass	186.0448
Grade	Reference Standard
HSN code	38229090
InChIKey	WWHJLVMBXXXUFO-UHFFFAOYSA-N
SMILES	COC1=C(C=C(C=C1)CCl)OC
PubChem CID	81740

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	0 / 2
TPSA	18.5 Å²
Synonyms	Veratryl chloride, Benzene, 4-(chloromethyl)-1,2-dimethoxy-, 4-(Chloromethyl)-1,2-dimethoxy benzene, alpha-Chloro-3,4-dimethoxytoluene, 4-(chloromethyl)-1,2-dimethoxy-benzene, Veratryl chlorid, 3,4-Bis(methoxy)-benzyl chloride, Toluene, alpha-chloro-3,4-dimethoxy-

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H314Causes severe skin burns and eye damage
H317May cause an allergic skin reaction
H335May cause respiratory irritation

Precautionary statements: P260, P261, P264, P270, P271, P272, P280, P301 + P317, P301 + P330 + P331, P302 + P352, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P319, P321, P330, P333 + P317, P362 + P364, P363, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3, 4-Dimethoxybenzyl chloride?

The CAS Registry Number of 3, 4-Dimethoxybenzyl chloride is 7306-46-9. It is also known as Veratryl chloride, Benzene, 4-(chloromethyl)-1,2-dimethoxy-, 4-(Chloromethyl)-1,2-dimethoxy benzene.

What is the molecular formula and molecular weight of 3, 4-Dimethoxybenzyl chloride?

3, 4-Dimethoxybenzyl chloride has the molecular formula C9H11ClO2 and a molecular weight of 186.63 g/mol. Its IUPAC name is 4-(chloromethyl)-1,2-dimethoxybenzene.

What is 3, 4-Dimethoxybenzyl chloride used for?

3, 4-Dimethoxybenzyl chloride is supplied as a characterised reference material related to Verapamil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3, 4-Dimethoxybenzyl chloride can I order?

We supply 3, 4-Dimethoxybenzyl chloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3, 4-Dimethoxybenzyl chloride?

Yes. Every lot of 3, 4-Dimethoxybenzyl chloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3, 4-Dimethoxybenzyl chloride be shipped internationally?

Yes. 3, 4-Dimethoxybenzyl chloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.