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3-Carbamoyl-1-(4-methoxyphenyl)-4-(2-(4-(2-oxopiperidin-1-yl)phenylamino)ethyl)-1H-pyrazole-5-carboxylic Acid

CAS No.2206825-81-0
FormulaC25H27N5O5
Mol. weight477.50
Catalogue No.VQ-024315
PurityReference Standard
HSN38229090

3-Carbamoyl-1-(4-methoxyphenyl)-4-(2-(4-(2-oxopiperidin-1-yl)phenylamino)ethyl)-1H-pyrazole-5-carboxylic Acid (CAS 2206825-81-0) – Apixaban impurity standard.

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About 3-Carbamoyl-1-(4-methoxyphenyl)-4-(2-(4-(2-oxopiperidin-1-yl)phenylamino)ethyl)-1H-pyrazole-5-carboxylic Acid

3-Carbamoyl-1-(4-methoxyphenyl)-4-(2-(4-(2-oxopiperidin-1-yl)phenylamino)ethyl)-1H-pyrazole-5-carboxylic Acid is an impurity of Apixaban carrying the CAS registry number 2206825-81-0. The compound has the formula C25H27N5O5, corresponding to a molecular weight of 477.5 g/mol. Its systematic (IUPAC) name is 3-carbamoyl-1-(4-methoxyphenyl)-4-[2-[4-(2-oxopiperidin-1-yl)anilino]ethyl]pyrazole-5-carboxylic acid.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Apixaban to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 3-Carbamoyl-1-(4-methoxyphenyl)-4-(2-(4-(2-oxopiperidin-1-yl)phenylamino)ethyl)-1H-pyrazole-5-carboxylic Acid in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Industries

Related to Apixaban

View every impurity, metabolite and intermediate we list for Apixaban.

Apixaban impurities

Specifications & identifiers

Chemical identifiers
Product name3-Carbamoyl-1-(4-methoxyphenyl)-4-(2-(4-(2-oxopiperidin-1-yl)phenylamino)ethyl)-1H-pyrazole-5-carboxylic Acid
Catalogue No.VQ-024315
CAS Number2206825-81-0
IUPAC name3-carbamoyl-1-(4-methoxyphenyl)-4-[2-[4-(2-oxopiperidin-1-yl)anilino]ethyl]pyrazole-5-carboxylic acid
Molecular formulaC25H27N5O5
Molecular weight477.5 g/mol
Exact mass477.2012
GradeReference Standard
HSN code38229090
InChIKeyULIINFDDZREUCC-UHFFFAOYSA-N
SMILESCOC1=CC=C(C=C1)N2C(=C(C(=N2)C(=O)N)CCNC3=CC=C(C=C3)N4CCCCC4=O)C(=O)O
PubChem CID163203152
Physical properties
Physical formSolid
LogP (XLogP3)2.7
H-bond donors / acceptors3 / 7
TPSA140 Ų

Documents

Frequently asked questions

What is the CAS number of 3-Carbamoyl-1-(4-methoxyphenyl)-4-(2-(4-(2-oxopiperidin-1-yl)phenylamino)ethyl)-1H-pyrazole-5-carboxylic Acid?

The CAS Registry Number of 3-Carbamoyl-1-(4-methoxyphenyl)-4-(2-(4-(2-oxopiperidin-1-yl)phenylamino)ethyl)-1H-pyrazole-5-carboxylic Acid is 2206825-81-0.

What is the molecular formula and molecular weight of 3-Carbamoyl-1-(4-methoxyphenyl)-4-(2-(4-(2-oxopiperidin-1-yl)phenylamino)ethyl)-1H-pyrazole-5-carboxylic Acid?

3-Carbamoyl-1-(4-methoxyphenyl)-4-(2-(4-(2-oxopiperidin-1-yl)phenylamino)ethyl)-1H-pyrazole-5-carboxylic Acid has the molecular formula C25H27N5O5 and a molecular weight of 477.5 g/mol. Its IUPAC name is 3-carbamoyl-1-(4-methoxyphenyl)-4-[2-[4-(2-oxopiperidin-1-yl)anilino]ethyl]pyrazole-5-carboxylic acid.

What is 3-Carbamoyl-1-(4-methoxyphenyl)-4-(2-(4-(2-oxopiperidin-1-yl)phenylamino)ethyl)-1H-pyrazole-5-carboxylic Acid used for?

3-Carbamoyl-1-(4-methoxyphenyl)-4-(2-(4-(2-oxopiperidin-1-yl)phenylamino)ethyl)-1H-pyrazole-5-carboxylic Acid is supplied as a characterised reference material related to Apixaban. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-Carbamoyl-1-(4-methoxyphenyl)-4-(2-(4-(2-oxopiperidin-1-yl)phenylamino)ethyl)-1H-pyrazole-5-carboxylic Acid can I order?

We supply 3-Carbamoyl-1-(4-methoxyphenyl)-4-(2-(4-(2-oxopiperidin-1-yl)phenylamino)ethyl)-1H-pyrazole-5-carboxylic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-Carbamoyl-1-(4-methoxyphenyl)-4-(2-(4-(2-oxopiperidin-1-yl)phenylamino)ethyl)-1H-pyrazole-5-carboxylic Acid?

Yes. Every lot of 3-Carbamoyl-1-(4-methoxyphenyl)-4-(2-(4-(2-oxopiperidin-1-yl)phenylamino)ethyl)-1H-pyrazole-5-carboxylic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-Carbamoyl-1-(4-methoxyphenyl)-4-(2-(4-(2-oxopiperidin-1-yl)phenylamino)ethyl)-1H-pyrazole-5-carboxylic Acid be shipped internationally?

Yes. We export 3-Carbamoyl-1-(4-methoxyphenyl)-4-(2-(4-(2-oxopiperidin-1-yl)phenylamino)ethyl)-1H-pyrazole-5-carboxylic Acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.

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