3-Chloro-4-(trifluoromethayl)-2-pyridinamine 1227513-97-4

Name: 3-Chloro-4-(trifluoromethayl)-2-pyridinamine
Brand: Vaqora Chemicals
SKU: VQ-042630

About 3-Chloro-4-(trifluoromethayl)-2-pyridinamine

3-Chloro-4-(trifluoromethayl)-2-pyridinamine (CAS 1227513-97-4) is an impurity of Tovorafenib offered by Vaqora Chemicals. Formula C6H4ClF3N2, molecular weight 196.56 g/mol. Its systematic (IUPAC) name is 3-chloro-4-(trifluoromethyl)pyridin-2-amine.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This Tovorafenib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 3-Chloro-4-(trifluoromethayl)-2-pyridinamine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Tovorafenib

View every impurity, metabolite and intermediate we list for Tovorafenib.

Tovorafenib impurities

Specifications & identifiers

Chemical identifiers
Product name	3-Chloro-4-(trifluoromethayl)-2-pyridinamine
Catalogue No.	VQ-042630
CAS Number	1227513-97-4
IUPAC name	3-chloro-4-(trifluoromethyl)pyridin-2-amine
Molecular formula	C₆H₄ClF₃N₂
Molecular weight	196.56 g/mol
Exact mass	196.0015
Grade	Reference Standard
HSN code	38229090
InChIKey	NINXGROOEMZYSZ-UHFFFAOYSA-N
SMILES	C1=CN=C(C(=C1C(F)(F)F)Cl)N
PubChem CID	72212787

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	1 / 5
TPSA	38.9 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-Chloro-4-(trifluoromethayl)-2-pyridinamine?

The CAS Registry Number of 3-Chloro-4-(trifluoromethayl)-2-pyridinamine is 1227513-97-4.

What is the molecular formula and molecular weight of 3-Chloro-4-(trifluoromethayl)-2-pyridinamine?

3-Chloro-4-(trifluoromethayl)-2-pyridinamine has the molecular formula C6H4ClF3N2 and a molecular weight of 196.56 g/mol. Its IUPAC name is 3-chloro-4-(trifluoromethyl)pyridin-2-amine.

What is 3-Chloro-4-(trifluoromethayl)-2-pyridinamine used for?

3-Chloro-4-(trifluoromethayl)-2-pyridinamine is supplied as a characterised reference material related to Tovorafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-Chloro-4-(trifluoromethayl)-2-pyridinamine can I order?

We supply 3-Chloro-4-(trifluoromethayl)-2-pyridinamine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-Chloro-4-(trifluoromethayl)-2-pyridinamine?

Yes. Every lot of 3-Chloro-4-(trifluoromethayl)-2-pyridinamine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-Chloro-4-(trifluoromethayl)-2-pyridinamine be shipped internationally?

Yes. 3-Chloro-4-(trifluoromethayl)-2-pyridinamine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.