6-Chloro-4-pyrimidinecarboxylic acid

Name: 6-Chloro-4-pyrimidinecarboxylic acid
Brand: Vaqora Chemicals
SKU: VQ-042634

About 6-Chloro-4-pyrimidinecarboxylic acid

6-Chloro-4-pyrimidinecarboxylic acid (CAS 37131-91-2) is an impurity of Tovorafenib offered by Vaqora Chemicals. The compound has the formula C5H3ClN2O2, corresponding to a molecular weight of 158.54 g/mol. Systematically, it is named 6-chloropyrimidine-4-carboxylic acid. It is also known as 4-Pyrimidinecarboxylic acid, 6-chloro- or 4-carboxy-6-chloropyrimidine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Tovorafenib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 6-Chloro-4-pyrimidinecarboxylic acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Tovorafenib

View every impurity, metabolite and intermediate we list for Tovorafenib.

Tovorafenib impurities

Specifications & identifiers

Chemical identifiers
Product name	6-Chloro-4-pyrimidinecarboxylic acid
Catalogue No.	VQ-042634
CAS Number	37131-91-2
IUPAC name	6-chloropyrimidine-4-carboxylic acid
Molecular formula	C₅H₃ClN₂O₂
Molecular weight	158.54 g/mol
Exact mass	157.9883
Grade	Reference Standard
HSN code	38229090
InChIKey	RWSPRTBXAXZIOS-UHFFFAOYSA-N
SMILES	C1=C(N=CN=C1Cl)C(=O)O
PubChem CID	16637747

Physical properties
Physical form	Solid
LogP (XLogP3)	1
H-bond donors / acceptors	1 / 4
TPSA	63.1 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 6-Chloro-4-pyrimidinecarboxylic acid?

The CAS Registry Number of 6-Chloro-4-pyrimidinecarboxylic acid is 37131-91-2. It is also known as 4-Pyrimidinecarboxylic acid, 6-chloro-, 4-carboxy-6-chloropyrimidine, 4-Pyrimidin.

What is the molecular formula and molecular weight of 6-Chloro-4-pyrimidinecarboxylic acid?

6-Chloro-4-pyrimidinecarboxylic acid has the molecular formula C5H3ClN2O2 and a molecular weight of 158.54 g/mol. Its IUPAC name is 6-chloropyrimidine-4-carboxylic acid.

What is 6-Chloro-4-pyrimidinecarboxylic acid used for?

6-Chloro-4-pyrimidinecarboxylic acid is supplied as a characterised reference material related to Tovorafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 6-Chloro-4-pyrimidinecarboxylic acid can I order?

We supply 6-Chloro-4-pyrimidinecarboxylic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 6-Chloro-4-pyrimidinecarboxylic acid?

Yes. Every lot of 6-Chloro-4-pyrimidinecarboxylic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 6-Chloro-4-pyrimidinecarboxylic acid be shipped internationally?

Yes. We export 6-Chloro-4-pyrimidinecarboxylic acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.