3-Demethyl Thiocolchicine-d3

Name: 3-Demethyl Thiocolchicine-d3
Brand: Vaqora Chemicals
SKU: VQ-042495

About 3-Demethyl Thiocolchicine-d3

3-Demethyl Thiocolchicine-d3 (CAS 1246818-03-0) is a stable isotope labelled analogue related to Thiocolchicine offered by Vaqora Chemicals. Its molecular formula is C21H23NO5S and its molecular weight is 404.5 g/mol. Common synonyms include 3-O-Desmethyl Thiocolchicine D3.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Thiocolchicine and related analytes in bioanalytical, pharmacokinetic and impurity studies. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer 3-Demethyl Thiocolchicine-d3 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Thiocolchicine

View every impurity, metabolite and intermediate we list for Thiocolchicine.

Thiocolchicine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	3-Demethyl Thiocolchicine-d3
Catalogue No.	VQ-042495
CAS Number	1246818-03-0
IUPAC name	2,2,2-trideuterio-N-[(7S)-3-hydroxy-1,2-dimethoxy-10-methylsulfanyl-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
Molecular formula	C₂₁H₂₃NO₅S
Molecular weight	404.5 g/mol
Exact mass	404.1485
Grade	Reference Standard
HSN code	38229090
InChIKey	PKYOHQGXPPVIGD-VSLDJYOXSA-N
SMILES	[2H]C([2H])([2H])C(=O)N[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)SC)OC)OC)O
PubChem CID	53312103

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	2 / 6
TPSA	110 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-Demethyl Thiocolchicine-d3?

The CAS Registry Number of 3-Demethyl Thiocolchicine-d3 is 1246818-03-0. It is also known as 3-O-Desmethyl Thiocolchicine D3.

What is the molecular formula and molecular weight of 3-Demethyl Thiocolchicine-d3?

3-Demethyl Thiocolchicine-d3 has the molecular formula C21H23NO5S and a molecular weight of 404.5 g/mol. Its IUPAC name is 2,2,2-trideuterio-N-[(7S)-3-hydroxy-1,2-dimethoxy-10-methylsulfanyl-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide.

What is 3-Demethyl Thiocolchicine-d3 used for?

3-Demethyl Thiocolchicine-d3 is supplied as a characterised reference material related to Thiocolchicine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-Demethyl Thiocolchicine-d3 can I order?

We supply 3-Demethyl Thiocolchicine-d3 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-Demethyl Thiocolchicine-d3?

Yes. Every lot of 3-Demethyl Thiocolchicine-d3 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-Demethyl Thiocolchicine-d3 be shipped internationally?

Yes. We export 3-Demethyl Thiocolchicine-d3 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.