3-Iodo-L-tyrosine

Name: 3-Iodo-L-tyrosine
Brand: Vaqora Chemicals
SKU: VQ-013025

About 3-Iodo-L-tyrosine

Listed under CAS 70-78-0, 3-Iodo-L-tyrosine is a process intermediate or related compound of Levothyroxine available from Vaqora Chemicals. With the molecular formula C9H10INO3, it has a molar mass of 307.08 g/mol. The IUPAC name is (2S)-2-amino-3-(4-hydroxy-3-iodophenyl)propanoic acid. Common synonyms include 3-Iodo-4-hydroxyphenylalanine and 3-Iodotyrosine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

It is a process intermediate or related compound in the synthesis of Levothyroxine, useful for route development, impurity fate-and-purge studies and analytical method development. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Levothyroxine

View every impurity, metabolite and intermediate we list for Levothyroxine.

Levothyroxine impurities

Specifications & identifiers

Chemical identifiers
Product name	3-Iodo-L-tyrosine
Catalogue No.	VQ-013025
CAS Number	70-78-0
IUPAC name	(2S)-2-amino-3-(4-hydroxy-3-iodophenyl)propanoic acid
Molecular formula	C₉H₁₀INO₃
Molecular weight	307.08 g/mol
Exact mass	306.9705
Grade	Reference Standard
HSN code	2933
InChIKey	UQTZMGFTRHFAAM-ZETCQYMHSA-N
SMILES	C1=CC(=C(C=C1C[C@@H](C(=O)O)N)I)O
PubChem CID	439744

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.1
H-bond donors / acceptors	3 / 4
TPSA	83.6 Å²
Synonyms	3-Iodo-4-hydroxyphenylalanine, 3-Iodotyrosine, 4-Hydroxy-3-iodophenylalanine, MIT, MIT (amino acid), (S)-2-Amino-3-(4-hydroxy-3-iodophenyl)propanoic Acid, L-Tyrosine, 3-iodo-, Tyrosine, 3-iodo-, L-, 2-amino-3-(4-hydroxy-3-iodophenyl)propanoic acid, H-Tyr(3-I)-OH, Monoiodotyrosine, 3-Monoiodo-L-tyrosine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-Iodo-L-tyrosine?

The CAS Registry Number of 3-Iodo-L-tyrosine is 70-78-0. It is also known as 3-Iodo-4-hydroxyphenylalanine, 3-Iodotyrosine, 4-Hydroxy-3-iodophenylalanine.

What is the molecular formula and molecular weight of 3-Iodo-L-tyrosine?

3-Iodo-L-tyrosine has the molecular formula C9H10INO3 and a molecular weight of 307.08 g/mol. Its IUPAC name is (2S)-2-amino-3-(4-hydroxy-3-iodophenyl)propanoic acid.

What is 3-Iodo-L-tyrosine used for?

3-Iodo-L-tyrosine is supplied as a characterised reference material related to Levothyroxine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-Iodo-L-tyrosine can I order?

We supply 3-Iodo-L-tyrosine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-Iodo-L-tyrosine?

Yes. Every lot of 3-Iodo-L-tyrosine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-Iodo-L-tyrosine be shipped internationally?

Yes. 3-Iodo-L-tyrosine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.