Levothyroxine N-Methylamide

Name: Levothyroxine N-Methylamide
Brand: Vaqora Chemicals
SKU: VQ-013520

About Levothyroxine N-Methylamide

Levothyroxine N-Methylamide (CAS 2088032-52-2) is a process intermediate or related compound of Levothyroxine offered by Vaqora Chemicals at a purity of 96%. Formula C16H14I4N2O3, molecular weight 789.91 g/mol. Its systematic (IUPAC) name is (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-N-methylpropanamide. It is also known as L-Thyroxine-N-methylamide.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Process chemists and analysts use it when developing synthetic routes to Levothyroxine, tracking process-related impurities and validating analytical methods. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Levothyroxine

View every impurity, metabolite and intermediate we list for Levothyroxine.

Levothyroxine impurities

Specifications & identifiers

Chemical identifiers
Product name	Levothyroxine N-Methylamide
Catalogue No.	VQ-013520
CAS Number	2088032-52-2
IUPAC name	(2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-N-methylpropanamide
Molecular formula	C₁₆H₁₄I₄N₂O₃
Molecular weight	789.91 g/mol
Exact mass	789.7183
Grade	Reference Standard
Purity / assay	96%
HSN code	2933
InChIKey	KRYBBJJOQJVIIZ-ZDUSSCGKSA-N
SMILES	CNC(=O)[C@H](CC1=CC(=C(C(=C1)I)OC2=CC(=C(C(=C2)I)O)I)I)N
PubChem CID	76957581

Physical properties
Physical form	Solid
LogP (XLogP3)	4.4
H-bond donors / acceptors	3 / 4
TPSA	84.6 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Levothyroxine N-Methylamide?

The CAS Registry Number of Levothyroxine N-Methylamide is 2088032-52-2. It is also known as (S)-2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)-N-methylpropanamide, (αS)-α-Amino-4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-N-methylbenzenepropanamide, L-Thyroxine-N-methylamide.

What is the molecular formula and molecular weight of Levothyroxine N-Methylamide?

Levothyroxine N-Methylamide has the molecular formula C16H14I4N2O3 and a molecular weight of 789.91 g/mol. Its IUPAC name is (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-N-methylpropanamide.

What is Levothyroxine N-Methylamide used for?

Levothyroxine N-Methylamide is supplied as a characterised reference material related to Levothyroxine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Levothyroxine N-Methylamide can I order?

We supply Levothyroxine N-Methylamide in Reference Standard (96%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Levothyroxine N-Methylamide?

Yes. Every lot of Levothyroxine N-Methylamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Levothyroxine N-Methylamide be shipped internationally?

Yes. We export Levothyroxine N-Methylamide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.