3-(Methylnitrosamino)propionitrile

Name: 3-(Methylnitrosamino)propionitrile
Brand: Vaqora Chemicals
SKU: VQ-026094

About 3-(Methylnitrosamino)propionitrile

3-(Methylnitrosamino)propionitrile is a nitrosamine impurity of Ibandronic acid carrying the CAS registry number 60153-49-3. The compound has the formula C4H7N3O, corresponding to a molecular weight of 113.12 g/mol. Systematically, it is named N-(2-cyanoethyl)-N-methylnitrous amide. It is also known as N-Nitroso 3-(methylamino)propionitrile or 3-(N-Nitrosomethylamino)propionitrile.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

Laboratories use this nitrosamine standard to develop and validate highly sensitive LC-MS/MS methods, to confirm limits of detection and to document nitrosamine risk assessments in regulatory submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 3-(Methylnitrosamino)propionitrile in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Ibandronic acid

View every impurity, metabolite and intermediate we list for Ibandronic acid.

Ibandronic acid impurities

Specifications & identifiers

Chemical identifiers
Product name	3-(Methylnitrosamino)propionitrile
Catalogue No.	VQ-026094
CAS Number	60153-49-3
IUPAC name	N-(2-cyanoethyl)-N-methylnitrous amide
Molecular formula	C₄H₇N₃O
Molecular weight	113.12 g/mol
Exact mass	113.0589
Grade	Reference Standard
HSN code	38229090
InChIKey	HZDLDFBKYBGNHG-UHFFFAOYSA-N
SMILES	CN(CCC#N)N=O
PubChem CID	62163

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.1
H-bond donors / acceptors	0 / 4
TPSA	56.5 Å²
Synonyms	N-Nitroso 3-(methylamino)propionitrile, 3-(N-Nitrosomethylamino)propionitrile, 3-(Methylnitrosoamino)propanenitrile, Propanenitrile, 3-(methylnitrosoamino)-, Propionitrile, 3-(methylnitrosamino)-, Propanenitrile, 3-(methylnitrosoamino)-, (4alpha)-, Propionitrile, 3-(methylnitrosamino)., 3-[methyl(nitroso)amino]propanenitrile, 3-(N-Nitrosomethylamino)propio-nitrile, (2-Cyanoethyl)methylnitrosamine, N-(2-Cyanoethyl)-N-methylnitrosamine

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H351Suspected of causing cancer

Precautionary statements: P203, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-(Methylnitrosamino)propionitrile?

The CAS Registry Number of 3-(Methylnitrosamino)propionitrile is 60153-49-3. It is also known as N-Nitroso 3-(methylamino)propionitrile, 3-(N-Nitrosomethylamino)propionitrile, 3-(Methylnitrosoamino)propanenitrile.

What is the molecular formula and molecular weight of 3-(Methylnitrosamino)propionitrile?

3-(Methylnitrosamino)propionitrile has the molecular formula C4H7N3O and a molecular weight of 113.12 g/mol. Its IUPAC name is N-(2-cyanoethyl)-N-methylnitrous amide.

What is 3-(Methylnitrosamino)propionitrile used for?

3-(Methylnitrosamino)propionitrile is supplied as a characterised reference material related to Ibandronic acid. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-(Methylnitrosamino)propionitrile can I order?

We supply 3-(Methylnitrosamino)propionitrile in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-(Methylnitrosamino)propionitrile?

Yes. Every lot of 3-(Methylnitrosamino)propionitrile is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-(Methylnitrosamino)propionitrile be shipped internationally?

Yes. 3-(Methylnitrosamino)propionitrile is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.