3''-O-Demethyl ivermectin

Name: 3''-O-Demethyl ivermectin
Brand: Vaqora Chemicals
SKU: VQ-031345

About 3''-O-Demethyl ivermectin

Listed under CAS 92137-95-6, 3''-O-Demethyl ivermectin is a metabolite or degradation product of Ivermectin available from Vaqora Chemicals. Its molecular formula is C47H72O14 and its molecular weight is 861.1 g/mol. It is also known as 3''-O-Desmethyldihydroavermectin B1a.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Ivermectin, as well as in QC testing and ANDA/DMF documentation. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 3''-O-Demethyl ivermectin is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Ivermectin

View every impurity, metabolite and intermediate we list for Ivermectin.

Ivermectin impurities

Specifications & identifiers

Chemical identifiers
Product name	3''-O-Demethyl ivermectin
Catalogue No.	VQ-031345
CAS Number	92137-95-6
IUPAC name	(1R,4S,5'S,6R,6'R,8R,10Z,12S,13S,14Z,20R,21R,24S)-6'-[(2S)-butan-2-yl]-12-[(2R,4S,5S,6S)-5-[(2S,4S,5R,6S)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-21,24-dihydroxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one
Molecular formula	C₄₇H₇₂O₁₄
Molecular weight	861.1 g/mol
Exact mass	860.4922
Grade	Reference Standard
HSN code	38229090
InChIKey	NMQZPTGPMUJFGY-ZHAVRHPHSA-N
SMILES	CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(\[C@H]([C@H](/C=C\C=C4CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)O)OC)/C)C
PubChem CID	154727831

Physical properties
Physical form	Solid
LogP (XLogP3)	3.6
H-bond donors / acceptors	4 / 14
TPSA	181 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3''-O-Demethyl ivermectin?

The CAS Registry Number of 3''-O-Demethyl ivermectin is 92137-95-6. It is also known as 3''-O-Desmethyldihydroavermectin B1a.

What is the molecular formula and molecular weight of 3''-O-Demethyl ivermectin?

3''-O-Demethyl ivermectin has the molecular formula C47H72O14 and a molecular weight of 861.1 g/mol.

What is 3''-O-Demethyl ivermectin used for?

3''-O-Demethyl ivermectin is supplied as a characterised reference material related to Ivermectin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3''-O-Demethyl ivermectin can I order?

We supply 3''-O-Demethyl ivermectin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3''-O-Demethyl ivermectin?

Yes. Every lot of 3''-O-Demethyl ivermectin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3''-O-Demethyl ivermectin be shipped internationally?

Yes. We export 3''-O-Demethyl ivermectin worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.