3-O Demethyl Staurosporine

Name: 3-O Demethyl Staurosporine
Brand: Vaqora Chemicals
SKU: VQ-031894

About 3-O Demethyl Staurosporine

3-O Demethyl Staurosporine is a metabolite or degradation product of Midostaurin carrying the CAS registry number 161743-35-7. With the molecular formula C27H24N4O3, it has a molar mass of 452.5 g/mol. It is also known as 3'-O-Desmethyl Staurosporine or 3'-Demethylstaurosporine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Midostaurin, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Midostaurin

View every impurity, metabolite and intermediate we list for Midostaurin.

Midostaurin impurities

Specifications & identifiers

Chemical identifiers
Product name	3-O Demethyl Staurosporine
Catalogue No.	VQ-031894
CAS Number	161743-35-7
IUPAC name	(2S,3R,4R,6R)-3-hydroxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-16-one
Molecular formula	C₂₇H₂₄N₄O₃
Molecular weight	452.5 g/mol
Exact mass	452.1848
Grade	Reference Standard
HSN code	38229090
InChIKey	YFYYWLWHOINTHH-FCHZLITKSA-N
SMILES	C[C@@]12[C@@H]([C@@H](C[C@@H](O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)O
PubChem CID	10049525

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	3 / 4
TPSA	80.5 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-O Demethyl Staurosporine?

The CAS Registry Number of 3-O Demethyl Staurosporine is 161743-35-7. It is also known as 3'-O-Desmethyl Staurosporine, 3'-Demethylstaurosporine, 3'-Demethoxy-3'-hydroxystaurosporine.

What is the molecular formula and molecular weight of 3-O Demethyl Staurosporine?

3-O Demethyl Staurosporine has the molecular formula C27H24N4O3 and a molecular weight of 452.5 g/mol.

What is 3-O Demethyl Staurosporine used for?

3-O Demethyl Staurosporine is supplied as a characterised reference material related to Midostaurin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-O Demethyl Staurosporine can I order?

We supply 3-O Demethyl Staurosporine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-O Demethyl Staurosporine?

Yes. Every lot of 3-O Demethyl Staurosporine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-O Demethyl Staurosporine be shipped internationally?

Yes. We export 3-O Demethyl Staurosporine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.