O-Desmethyl Midostaurin

Name: O-Desmethyl Midostaurin
Brand: Vaqora Chemicals
SKU: VQ-026689

About O-Desmethyl Midostaurin

O-Desmethyl Midostaurin is a metabolite or degradation product of Midostaurin carrying the CAS registry number 740816-86-8. The compound has the formula C34H28N4O4, corresponding to a molecular weight of 556.6 g/mol. Common synonyms include o-Desmethyl-pkc 412 and O-Desmethyl Midostaurin (CGP62221).

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Midostaurin, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, O-Desmethyl Midostaurin is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Midostaurin

View every impurity, metabolite and intermediate we list for Midostaurin.

Midostaurin impurities

Specifications & identifiers

Chemical identifiers
Product name	O-Desmethyl Midostaurin
Catalogue No.	VQ-026689
CAS Number	740816-86-8
IUPAC name	N-[(2S,3R,4R,6R)-3-hydroxy-2-methyl-16-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-4-yl]-N-methylbenzamide
Molecular formula	C₃₄H₂₈N₄O₄
Molecular weight	556.6 g/mol
Exact mass	556.2111
Grade	Reference Standard
HSN code	38229090
InChIKey	PXOCRDZEEXVZQC-AFUPZKSLSA-N
SMILES	C[C@@]12[C@@H]([C@@H](C[C@@H](O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)N(C)C(=O)C9=CC=CC=C9)O
PubChem CID	11261445

Physical properties
Physical form	Solid
LogP (XLogP3)	4.3
H-bond donors / acceptors	2 / 4
TPSA	88.7 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of O-Desmethyl Midostaurin?

The CAS Registry Number of O-Desmethyl Midostaurin is 740816-86-8. It is also known as o-Desmethyl-pkc 412, O-Desmethyl Midostaurin (CGP62221).

What is the molecular formula and molecular weight of O-Desmethyl Midostaurin?

O-Desmethyl Midostaurin has the molecular formula C34H28N4O4 and a molecular weight of 556.6 g/mol.

What is O-Desmethyl Midostaurin used for?

O-Desmethyl Midostaurin is supplied as a characterised reference material related to Midostaurin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of O-Desmethyl Midostaurin can I order?

We supply O-Desmethyl Midostaurin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with O-Desmethyl Midostaurin?

Yes. Every lot of O-Desmethyl Midostaurin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can O-Desmethyl Midostaurin be shipped internationally?

Yes. We export O-Desmethyl Midostaurin worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.