3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl ac… 179688-53-0

Name: 3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate
Brand: Vaqora Chemicals
SKU: VQ-030954

About 3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate

Vaqora Chemicals supplies 3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate, a metabolite or degradation product of Gefitinib registered under CAS number 179688-53-0. With the molecular formula C11H10N2O4, it has a molar mass of 234.21 g/mol. Its systematic (IUPAC) name is (7-methoxy-4-oxo-3H-quinazolin-6-yl) acetate. It is also known as 6-Acetoxy-7-methoxy-3H-quinazolin-4-one or 6-(acetyloxy)-7-methoxy-4(3h)-quinazolinone.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Analytical teams use this compound to identify metabolites and degradants of Gefitinib, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer 3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Gefitinib

View every impurity, metabolite and intermediate we list for Gefitinib.

Gefitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate
Catalogue No.	VQ-030954
CAS Number	179688-53-0
IUPAC name	(7-methoxy-4-oxo-3H-quinazolin-6-yl) acetate
Molecular formula	C₁₁H₁₀N₂O₄
Molecular weight	234.21 g/mol
Exact mass	234.0641
Grade	Reference Standard
HSN code	38229090
InChIKey	SOLQIFINSOHAQD-UHFFFAOYSA-N
SMILES	CC(=O)OC1=C(C=C2C(=C1)C(=O)NC=N2)OC
PubChem CID	135681960

Physical properties
Physical form	Solid
LogP (XLogP3)	0.4
H-bond donors / acceptors	1 / 5
TPSA	77 Å²
Synonyms	4-Hydroxy-7-methoxyquinazolin-6-yl Ester Acetic Acid, 6-Acetoxy-7-methoxy-3H-quinazolin-4-one, 7-Methoxy-4-oxo-3,4-dihydroquinazolin-6-yl acetate, 7-Methoxy-4-oxo-1,4-dihydroquinazolin-6-yl acetate, 6-(acetyloxy)-7-methoxy-4(3h)-quinazolinone, (7-methoxy-4-oxo-1H-quinazolin-6-yl) acetate, 4(1H)-Quinazolinone, 6-(acetyloxy)-7-methoxy-, 6-acetoxy-7-methoxy-3,4-dihydroquinazolin-4-one, Acetic acid 4-hydroxy-7-methoxy-quinazolin-6-yl ester, 6-(Acetyloxy)-7-methoxyquinazolin-4(3H)-one, 6-Acetoxy-7-methoxy-4-quinazolinol

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation

Precautionary statements: P261, P264, P264 + P265, P272, P280, P302 + P352, P305 + P351 + P338, P321, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate?

The CAS Registry Number of 3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate is 179688-53-0. It is also known as 4-Hydroxy-7-methoxyquinazolin-6-yl Ester Acetic Acid, 6-Acetoxy-7-methoxy-3H-quinazolin-4-one, 7-Methoxy-4-oxo-3,4-dihydroquinazolin-6-yl acetate.

What is the molecular formula and molecular weight of 3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate?

3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate has the molecular formula C11H10N2O4 and a molecular weight of 234.21 g/mol. Its IUPAC name is (7-methoxy-4-oxo-3H-quinazolin-6-yl) acetate.

What is 3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate used for?

3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate is supplied as a characterised reference material related to Gefitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate can I order?

We supply 3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate?

Yes. Every lot of 3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate be shipped internationally?

Yes. 3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.