Gefitinib-d8

Name: Gefitinib-d8
Brand: Vaqora Chemicals
SKU: VQ-030957

About Gefitinib-d8

Listed under CAS 857091-32-8, Gefitinib-d8 is a stable isotope labelled analogue related to Gefitinib available from Vaqora Chemicals. The compound has the formula C22H24ClFN4O3, corresponding to a molecular weight of 454.9 g/mol.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Gefitinib and related analytes in bioanalytical, pharmacokinetic and impurity studies. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Gefitinib-d8 is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Gefitinib

View every impurity, metabolite and intermediate we list for Gefitinib.

Gefitinib impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Gefitinib-d8
Catalogue No.	VQ-030957
CAS Number	857091-32-8
IUPAC name	N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(2,2,3,3,5,5,6,6-octadeuteriomorpholin-4-yl)propoxy]quinazolin-4-amine
Molecular formula	C₂₂H₂₄ClFN₄O₃
Molecular weight	454.9 g/mol
Exact mass	454.2023
Grade	Reference Standard
HSN code	38229090
InChIKey	XGALLCVXEZPNRQ-IHGLQNJRSA-N
SMILES	[2H]C1(C(OC(C(N1CCCOC2=C(C=C3C(=C2)C(=NC=N3)NC4=CC(=C(C=C4)F)Cl)OC)([2H])[2H])([2H])[2H])([2H])[2H])[2H]
PubChem CID	49849312

Physical properties
Physical form	Solid
LogP (XLogP3)	4.1
H-bond donors / acceptors	1 / 8
TPSA	68.7 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Gefitinib-d8?

The CAS Registry Number of Gefitinib-d8 is 857091-32-8. It is also known as N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(morpholino-d8)propoxy)quinazolin-4-amine.

What is the molecular formula and molecular weight of Gefitinib-d8?

Gefitinib-d8 has the molecular formula C22H24ClFN4O3 and a molecular weight of 454.9 g/mol. Its IUPAC name is N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(2,2,3,3,5,5,6,6-octadeuteriomorpholin-4-yl)propoxy]quinazolin-4-amine.

What is Gefitinib-d8 used for?

Gefitinib-d8 is supplied as a characterised reference material related to Gefitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Gefitinib-d8 can I order?

We supply Gefitinib-d8 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Gefitinib-d8?

Yes. Every lot of Gefitinib-d8 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Gefitinib-d8 be shipped internationally?

Yes. We export Gefitinib-d8 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.