[(3R,3AS,6aR)-Hydroxyhexahydrofuro[2,3-b]fura… 253265-97-3

Name: [(3R,3AS,6aR)-Hydroxyhexahydrofuro[2,3-b]furanyl Succinimidyl Carbonate
Brand: Vaqora Chemicals
SKU: VQ-036567

About [(3R,3AS,6aR)-Hydroxyhexahydrofuro[2,3-b]furanyl Succinimidyl Carbonate

Vaqora Chemicals supplies [(3R,3AS,6aR)-Hydroxyhexahydrofuro[2,3-b]furanyl Succinimidyl Carbonate, a metabolite or degradation product of Darunavir registered under CAS number 253265-97-3. Formula C11H13NO7, molecular weight 271.22 g/mol. Systematically, it is named [(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] (2,5-dioxopyrrolidin-1-yl) carbonate. Alternative names: Bis furanol carbonate and BIS THF HNS Derivative 4.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 5 hazard statements. Review the Safety Data Sheet before use.

Analytical teams use this compound to identify metabolites and degradants of Darunavir, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies [(3R,3AS,6aR)-Hydroxyhexahydrofuro[2,3-b]furanyl Succinimidyl Carbonate in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Darunavir

View every impurity, metabolite and intermediate we list for Darunavir.

Darunavir impurities

Specifications & identifiers

Chemical identifiers
Product name	[(3R,3AS,6aR)-Hydroxyhexahydrofuro[2,3-b]furanyl Succinimidyl Carbonate
Catalogue No.	VQ-036567
CAS Number	253265-97-3
IUPAC name	[(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] (2,5-dioxopyrrolidin-1-yl) carbonate
Molecular formula	C₁₁H₁₃NO₇
Molecular weight	271.22 g/mol
Exact mass	271.0692
Grade	Reference Standard
HSN code	38229090
InChIKey	VCFNCYVHQSHFRH-MHYGZLNHSA-N
SMILES	C1CO[C@H]2[C@@H]1[C@H](CO2)OC(=O)ON3C(=O)CCC3=O
PubChem CID	11184820

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.3
H-bond donors / acceptors	0 / 7
TPSA	91.4 Å²
Synonyms	Bis furanol carbonate, 2,5-Dioxopyrrolidin-1-yl ((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl) carbonate, 2,5-Dioxopyrrolidin-1-yl ((3R,3aS,6aR)-hexahydrofuro(2,3-b)furan-3-yl) carbonate, 2,5-Dioxopyrrolidin-1-yl((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl)carbonate, BIS THF HNS Derivative 4, [(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl] (2,5-Dioxopyrrolidin-1-yl) Carbonate, EX-A12426G, 2,5-Dioxo-1-pyrrolidyl [(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl] Carbonate

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H318Causes serious eye damage
H341Suspected of causing genetic defects
H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P261, P264, P264 + P265, P270, P272, P280, P301 + P317, P302 + P352, P305 + P354 + P338, P317, P318, P321, P330, P333 + P317, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of [(3R,3AS,6aR)-Hydroxyhexahydrofuro[2,3-b]furanyl Succinimidyl Carbonate?

The CAS Registry Number of [(3R,3AS,6aR)-Hydroxyhexahydrofuro[2,3-b]furanyl Succinimidyl Carbonate is 253265-97-3. It is also known as Bis furanol carbonate, 2,5-Dioxopyrrolidin-1-yl ((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl) carbonate, 2,5-Dioxopyrrolidin-1-yl ((3R,3aS,6aR)-hexahydrofuro(2,3-b)furan-3-yl) carbonate.

What is the molecular formula and molecular weight of [(3R,3AS,6aR)-Hydroxyhexahydrofuro[2,3-b]furanyl Succinimidyl Carbonate?

[(3R,3AS,6aR)-Hydroxyhexahydrofuro[2,3-b]furanyl Succinimidyl Carbonate has the molecular formula C11H13NO7 and a molecular weight of 271.22 g/mol. Its IUPAC name is [(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] (2,5-dioxopyrrolidin-1-yl) carbonate.

What is [(3R,3AS,6aR)-Hydroxyhexahydrofuro[2,3-b]furanyl Succinimidyl Carbonate used for?

[(3R,3AS,6aR)-Hydroxyhexahydrofuro[2,3-b]furanyl Succinimidyl Carbonate is supplied as a characterised reference material related to Darunavir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of [(3R,3AS,6aR)-Hydroxyhexahydrofuro[2,3-b]furanyl Succinimidyl Carbonate can I order?

We supply [(3R,3AS,6aR)-Hydroxyhexahydrofuro[2,3-b]furanyl Succinimidyl Carbonate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with [(3R,3AS,6aR)-Hydroxyhexahydrofuro[2,3-b]furanyl Succinimidyl Carbonate?

Yes. Every lot of [(3R,3AS,6aR)-Hydroxyhexahydrofuro[2,3-b]furanyl Succinimidyl Carbonate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can [(3R,3AS,6aR)-Hydroxyhexahydrofuro[2,3-b]furanyl Succinimidyl Carbonate be shipped internationally?

Yes. [(3R,3AS,6aR)-Hydroxyhexahydrofuro[2,3-b]furanyl Succinimidyl Carbonate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.