3'(S)-Hydroxy Simvastatin

Name: 3'(S)-Hydroxy Simvastatin
Brand: Vaqora Chemicals
SKU: VQ-035076

About 3'(S)-Hydroxy Simvastatin

Vaqora Chemicals supplies 3'(S)-Hydroxy Simvastatin, a metabolite or degradation product of Simvastatin registered under CAS number 133645-46-2. Formula C25H38O6, molecular weight 434.6 g/mol. Alternative names: Simvastatin (6S)-Hydroxy Isomer and (6S)-Hydroxy Simvastatin.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Simvastatin, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Simvastatin

View every impurity, metabolite and intermediate we list for Simvastatin.

Simvastatin impurities

Specifications & identifiers

Chemical identifiers
Product name	3'(S)-Hydroxy Simvastatin
Catalogue No.	VQ-035076
CAS Number	133645-46-2
IUPAC name	[(1S,6S,7R,8S,8aR)-6-hydroxy-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl] 2,2-dimethylbutanoate
Molecular formula	C₂₅H₃₈O₆
Molecular weight	434.6 g/mol
Exact mass	434.2668
Grade	Reference Standard
HSN code	38229090
InChIKey	ZHTMJJNBYMYMRV-VVSCFXOTSA-N
SMILES	CCC(C)(C)C(=O)O[C@H]1CC(=CC2=C[C@H]([C@@H]([C@@H]([C@@H]12)CC[C@@H]3C[C@H](CC(=O)O3)O)C)O)C
PubChem CID	21728613

Physical properties
Physical form	Solid
LogP (XLogP3)	3.2
H-bond donors / acceptors	2 / 6
TPSA	93.1 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3'(S)-Hydroxy Simvastatin?

The CAS Registry Number of 3'(S)-Hydroxy Simvastatin is 133645-46-2. It is also known as Simvastatin (6S)-Hydroxy Isomer, (6S)-Hydroxy Simvastatin.

What is the molecular formula and molecular weight of 3'(S)-Hydroxy Simvastatin?

3'(S)-Hydroxy Simvastatin has the molecular formula C25H38O6 and a molecular weight of 434.6 g/mol. Its IUPAC name is [(1S,6S,7R,8S,8aR)-6-hydroxy-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl] 2,2-dimethylbutanoate.

What is 3'(S)-Hydroxy Simvastatin used for?

3'(S)-Hydroxy Simvastatin is supplied as a characterised reference material related to Simvastatin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3'(S)-Hydroxy Simvastatin can I order?

We supply 3'(S)-Hydroxy Simvastatin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3'(S)-Hydroxy Simvastatin?

Yes. Every lot of 3'(S)-Hydroxy Simvastatin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3'(S)-Hydroxy Simvastatin be shipped internationally?

Yes. We export 3'(S)-Hydroxy Simvastatin worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.