(3S,5S)-Dihydroxy Simvastatin

Name: (3S,5S)-Dihydroxy Simvastatin
Brand: Vaqora Chemicals
SKU: VQ-028043

About (3S,5S)-Dihydroxy Simvastatin

Listed under CAS 159143-77-8, (3S,5S)-Dihydroxy Simvastatin is an impurity of Simvastatin available from Vaqora Chemicals. With the molecular formula C25H40O7, it has a molar mass of 452.6 g/mol. Common synonyms include 3',5'-Dihydrodiol Simvastatin.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Simvastatin, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Simvastatin

View every impurity, metabolite and intermediate we list for Simvastatin.

Simvastatin impurities

Specifications & identifiers

Chemical identifiers
Product name	(3S,5S)-Dihydroxy Simvastatin
Catalogue No.	VQ-028043
CAS Number	159143-77-8
IUPAC name	[(1S,3R,7R,8S,8aR)-4,6-dihydroxy-8-[2-[(4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,4,6,7,8,8a-octahydronaphthalen-1-yl] 2,2-dimethylbutanoate
Molecular formula	C₂₅H₄₀O₇
Molecular weight	452.6 g/mol
Exact mass	452.2774
Grade	Reference Standard
HSN code	38229090
InChIKey	MRCKOKWQDZYFLT-GBCWWPGNSA-N
SMILES	CCC(C)(C)C(=O)O[C@H]1C[C@H](C(C2=CC([C@@H]([C@@H]([C@@H]12)CCC3C[C@H](CC(=O)O3)O)C)O)O)C
PubChem CID	71316234

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	3 / 7
TPSA	113 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (3S,5S)-Dihydroxy Simvastatin?

The CAS Registry Number of (3S,5S)-Dihydroxy Simvastatin is 159143-77-8. It is also known as 3',5'-Dihydrodiol Simvastatin.

What is the molecular formula and molecular weight of (3S,5S)-Dihydroxy Simvastatin?

(3S,5S)-Dihydroxy Simvastatin has the molecular formula C25H40O7 and a molecular weight of 452.6 g/mol. Its IUPAC name is [(1S,3R,7R,8S,8aR)-4,6-dihydroxy-8-[2-[(4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,4,6,7,8,8a-octahydronaphthalen-1-yl] 2,2-dimethylbutanoate.

What is (3S,5S)-Dihydroxy Simvastatin used for?

(3S,5S)-Dihydroxy Simvastatin is supplied as a characterised reference material related to Simvastatin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (3S,5S)-Dihydroxy Simvastatin can I order?

We supply (3S,5S)-Dihydroxy Simvastatin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (3S,5S)-Dihydroxy Simvastatin?

Yes. Every lot of (3S,5S)-Dihydroxy Simvastatin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (3S,5S)-Dihydroxy Simvastatin be shipped internationally?

Yes. We export (3S,5S)-Dihydroxy Simvastatin worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.