4-([1,2,4]Triazolo[1,5-a]pyridin-7-yloxy)-3-m… 937263-71-3

Name: 4-([1,2,4]Triazolo[1,5-a]pyridin-7-yloxy)-3-methylaniline
Brand: Vaqora Chemicals
SKU: VQ-034470

About 4-([1,2,4]Triazolo[1,5-a]pyridin-7-yloxy)-3-methylaniline

Listed under CAS 937263-71-3, 4-([1,2,4]Triazolo[1,5-a]pyridin-7-yloxy)-3-methylaniline is an impurity of Tucatinib available from Vaqora Chemicals. Formula C13H12N4O, molecular weight 240.26 g/mol. Systematically, it is named 3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)aniline. Common synonyms include Tucatimib intennediate.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Tucatinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 4-([1,2,4]Triazolo[1,5-a]pyridin-7-yloxy)-3-methylaniline in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Tucatinib

View every impurity, metabolite and intermediate we list for Tucatinib.

Tucatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	4-([1,2,4]Triazolo[1,5-a]pyridin-7-yloxy)-3-methylaniline
Catalogue No.	VQ-034470
CAS Number	937263-71-3
IUPAC name	3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)aniline
Molecular formula	C₁₃H₁₂N₄O
Molecular weight	240.26 g/mol
Exact mass	240.1011
Grade	Reference Standard
HSN code	38229090
InChIKey	DFMSLMUVJUMZPA-UHFFFAOYSA-N
SMILES	CC1=C(C=CC(=C1)N)OC2=CC3=NC=NN3C=C2
PubChem CID	66937013

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	1 / 4
TPSA	65.4 Å²
Synonyms	4-((1,2,4)Triazolo(1,5-a)pyrid-7-yloxy)-3-methylaniline, 4-([1,2,4]triazolo[1,5-a]pyrid-7-yloxy)-3-methylaniline, 3-methyl-4-{[1,2,4]triazolo[1,5-a]pyridin-7-yloxy}aniline, 3-Methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)benzenamine, 4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylbenzenamine, Benzenamine, 3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-, Tucatimib intennediate, -([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylaniline

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-([1,2,4]Triazolo[1,5-a]pyridin-7-yloxy)-3-methylaniline?

The CAS Registry Number of 4-([1,2,4]Triazolo[1,5-a]pyridin-7-yloxy)-3-methylaniline is 937263-71-3. It is also known as 4-((1,2,4)Triazolo(1,5-a)pyrid-7-yloxy)-3-methylaniline, 4-([1,2,4]triazolo[1,5-a]pyrid-7-yloxy)-3-methylaniline, 3-methyl-4-{[1,2,4]triazolo[1,5-a]pyridin-7-yloxy}aniline.

What is the molecular formula and molecular weight of 4-([1,2,4]Triazolo[1,5-a]pyridin-7-yloxy)-3-methylaniline?

4-([1,2,4]Triazolo[1,5-a]pyridin-7-yloxy)-3-methylaniline has the molecular formula C13H12N4O and a molecular weight of 240.26 g/mol. Its IUPAC name is 3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)aniline.

What is 4-([1,2,4]Triazolo[1,5-a]pyridin-7-yloxy)-3-methylaniline used for?

4-([1,2,4]Triazolo[1,5-a]pyridin-7-yloxy)-3-methylaniline is supplied as a characterised reference material related to Tucatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-([1,2,4]Triazolo[1,5-a]pyridin-7-yloxy)-3-methylaniline can I order?

We supply 4-([1,2,4]Triazolo[1,5-a]pyridin-7-yloxy)-3-methylaniline in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-([1,2,4]Triazolo[1,5-a]pyridin-7-yloxy)-3-methylaniline?

Yes. Every lot of 4-([1,2,4]Triazolo[1,5-a]pyridin-7-yloxy)-3-methylaniline is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-([1,2,4]Triazolo[1,5-a]pyridin-7-yloxy)-3-methylaniline be shipped internationally?

Yes. 4-([1,2,4]Triazolo[1,5-a]pyridin-7-yloxy)-3-methylaniline is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.