(E)-N'-(2-Cyano-4-nitrophenyl)-N,N-dimethylfo… 39263-34-8

Name: (E)-N'-(2-Cyano-4-nitrophenyl)-N,N-dimethylformimidamide
Brand: Vaqora Chemicals
SKU: VQ-044610

About (E)-N'-(2-Cyano-4-nitrophenyl)-N,N-dimethylformimidamide

(E)-N'-(2-Cyano-4-nitrophenyl)-N,N-dimethylformimidamide (CAS 39263-34-8) is an impurity of Tucatinib offered by Vaqora Chemicals. Its molecular formula is C10H10N4O2 and its molecular weight is 218.21 g/mol. Systematically, it is named N'-(2-cyano-4-nitrophenyl)-N,N-dimethylmethanimidamide. It is also known as nchembio866-comp21 or JS-199C.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This Tucatinib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies (E)-N'-(2-Cyano-4-nitrophenyl)-N,N-dimethylformimidamide in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Tucatinib

View every impurity, metabolite and intermediate we list for Tucatinib.

Tucatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	(E)-N'-(2-Cyano-4-nitrophenyl)-N,N-dimethylformimidamide
Catalogue No.	VQ-044610
CAS Number	39263-34-8
IUPAC name	N'-(2-cyano-4-nitrophenyl)-N,N-dimethylmethanimidamide
Molecular formula	C₁₀H₁₀N₄O₂
Molecular weight	218.21 g/mol
Exact mass	218.0804
Grade	Reference Standard
HSN code	38229090
InChIKey	RLSZPRPVHOOMBN-UHFFFAOYSA-N
SMILES	CN(C)C=NC1=C(C=C(C=C1)[N+](=O)[O-])C#N
PubChem CID	10900084

Physical properties
Physical form	Solid
LogP (XLogP3)	1.1
H-bond donors / acceptors	0 / 4
TPSA	85.2 Å²
Synonyms	N'-(2-Cyano-4-nitrophenyl)-N,N-dimethyliminoformamide, N'-(2-Cyano-4-nitrophenyl)-N,N-dimethylformamidine, N'-(2-Cyano-4-nitrophenyl)-N,N-dimethylformimidamide, nchembio866-comp21, JS-199C, (E)-N'-(2-cyano-4-nitrophenyl)-N,N-dimethylmethanimidamide, N'-(2-cyano-4-nitro-phenyl)-N,N-dimethylformamidine, (E)-N'-(2-cyano-4-nitrophenyl)-N,N-dimethylformamidine, N'-(2-cyano-4-nitro-phenyl)-N,N-dimethyl-formamidine, 2-{[(Dimethylamino)methylidene]amino}-5-nitrobenzonitrile, (1E)-N'-(2-Cyano-4-nitrophenyl)-N,N-dimethylmethanimidamide

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (E)-N'-(2-Cyano-4-nitrophenyl)-N,N-dimethylformimidamide?

The CAS Registry Number of (E)-N'-(2-Cyano-4-nitrophenyl)-N,N-dimethylformimidamide is 39263-34-8. It is also known as N'-(2-Cyano-4-nitrophenyl)-N,N-dimethyliminoformamide, N'-(2-Cyano-4-nitrophenyl)-N,N-dimethylformamidine, N'-(2-Cyano-4-nitrophenyl)-N,N-dimethylformimidamide.

What is the molecular formula and molecular weight of (E)-N'-(2-Cyano-4-nitrophenyl)-N,N-dimethylformimidamide?

(E)-N'-(2-Cyano-4-nitrophenyl)-N,N-dimethylformimidamide has the molecular formula C10H10N4O2 and a molecular weight of 218.21 g/mol. Its IUPAC name is N'-(2-cyano-4-nitrophenyl)-N,N-dimethylmethanimidamide.

What is (E)-N'-(2-Cyano-4-nitrophenyl)-N,N-dimethylformimidamide used for?

(E)-N'-(2-Cyano-4-nitrophenyl)-N,N-dimethylformimidamide is supplied as a characterised reference material related to Tucatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (E)-N'-(2-Cyano-4-nitrophenyl)-N,N-dimethylformimidamide can I order?

We supply (E)-N'-(2-Cyano-4-nitrophenyl)-N,N-dimethylformimidamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (E)-N'-(2-Cyano-4-nitrophenyl)-N,N-dimethylformimidamide?

Yes. Every lot of (E)-N'-(2-Cyano-4-nitrophenyl)-N,N-dimethylformimidamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (E)-N'-(2-Cyano-4-nitrophenyl)-N,N-dimethylformimidamide be shipped internationally?

Yes. (E)-N'-(2-Cyano-4-nitrophenyl)-N,N-dimethylformimidamide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.