4-Amino-3-chlorophenol

Name: 4-Amino-3-chlorophenol
Brand: Vaqora Chemicals
SKU: VQ-013079

About 4-Amino-3-chlorophenol

Listed under CAS 17609-80-2, 4-Amino-3-chlorophenol is a process intermediate or related compound of Lenvatinib available from Vaqora Chemicals. Formula C6H6ClNO, molecular weight 143.57 g/mol. Alternative names: 3-Chloro-4-aminophenol and 1-Hydroxy-4-amino-3-chlorobenzene.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

It is a process intermediate or related compound in the synthesis of Lenvatinib, useful for route development, impurity fate-and-purge studies and analytical method development. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 4-Amino-3-chlorophenol in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Lenvatinib

View every impurity, metabolite and intermediate we list for Lenvatinib.

Lenvatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Amino-3-chlorophenol
Catalogue No.	VQ-013079
CAS Number	17609-80-2
Other CAS	52671-64-4
IUPAC name	4-amino-3-chlorophenol
Molecular formula	C₆H₆ClNO
Molecular weight	143.57 g/mol
Exact mass	143.0138
Grade	Reference Standard
HSN code	2933
InChIKey	PNLPXABQLXSICH-UHFFFAOYSA-N
SMILES	C1=CC(=C(C=C1O)Cl)N
PubChem CID	87184

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	2 / 2
TPSA	46.3 Å²
Synonyms	3-Chloro-4-aminophenol, 1-Hydroxy-4-amino-3-chlorobenzene, 2-Chloro-4-hydroxyaniline, 3-Chloro-p-aminophenol, Phenol, 4-amino-3-chloro-, 4-amino-3-chloro-phenol, 4-amino-3-chloro-pheno, 3-13-00-01184 (Beilstein Handbook Reference)

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
H360May damage fertility or the unborn child
H400Very toxic to aquatic life

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P391, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Amino-3-chlorophenol?

The CAS Registry Number of 4-Amino-3-chlorophenol is 17609-80-2. It is also known as 3-Chloro-4-aminophenol, 1-Hydroxy-4-amino-3-chlorobenzene, 2-Chloro-4-hydroxyaniline.

What is the molecular formula and molecular weight of 4-Amino-3-chlorophenol?

4-Amino-3-chlorophenol has the molecular formula C6H6ClNO and a molecular weight of 143.57 g/mol. Its IUPAC name is 4-amino-3-chlorophenol.

What is 4-Amino-3-chlorophenol used for?

4-Amino-3-chlorophenol is supplied as a characterised reference material related to Lenvatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Amino-3-chlorophenol can I order?

We supply 4-Amino-3-chlorophenol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Amino-3-chlorophenol?

Yes. Every lot of 4-Amino-3-chlorophenol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Amino-3-chlorophenol be shipped internationally?

Yes. 4-Amino-3-chlorophenol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.