4-Chloro-7-methoxy-6-quinolinecarboxamide

Name: 4-Chloro-7-methoxy-6-quinolinecarboxamide
Brand: Vaqora Chemicals
SKU: VQ-013097

About 4-Chloro-7-methoxy-6-quinolinecarboxamide

4-Chloro-7-methoxy-6-quinolinecarboxamide is a process intermediate or related compound of Lenvatinib carrying the CAS registry number 417721-36-9. Its molecular formula is C11H9ClN2O2 and its molecular weight is 236.65 g/mol. The IUPAC name is 4-chloro-7-methoxyquinoline-6-carboxamide. Alternative names: 7-methoxy-4-chloro-quinoline-6-carboxamide and 6-Quinolinecarboxamide, 4-chloro-7-methoxy-.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Process chemists and analysts use it when developing synthetic routes to Lenvatinib, tracking process-related impurities and validating analytical methods. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Lenvatinib

View every impurity, metabolite and intermediate we list for Lenvatinib.

Lenvatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Chloro-7-methoxy-6-quinolinecarboxamide
Catalogue No.	VQ-013097
CAS Number	417721-36-9
IUPAC name	4-chloro-7-methoxyquinoline-6-carboxamide
Molecular formula	C₁₁H₉ClN₂O₂
Molecular weight	236.65 g/mol
Exact mass	236.0353
Grade	Reference Standard
HSN code	2933
InChIKey	ZBTVNIDMGKZSGC-UHFFFAOYSA-N
SMILES	COC1=CC2=NC=CC(=C2C=C1C(=O)N)Cl
PubChem CID	22936418

Physical properties
Physical form	Solid
LogP (XLogP3)	1.7
H-bond donors / acceptors	1 / 3
TPSA	65.2 Å²
Synonyms	7-methoxy-4-chloro-quinoline-6-carboxamide, 6-Quinolinecarboxamide, 4-chloro-7-methoxy-, 6-carbamoyl-4-chloro-7-methoxyquinoline, 7-Methoxy-4-chloroquinoline-6-carboxamide, 4-chloro-7-methoxy-quinoline-6-carboxamide

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Chloro-7-methoxy-6-quinolinecarboxamide?

The CAS Registry Number of 4-Chloro-7-methoxy-6-quinolinecarboxamide is 417721-36-9. It is also known as 7-methoxy-4-chloro-quinoline-6-carboxamide, 6-Quinolinecarboxamide, 4-chloro-7-methoxy-, 6-carbamoyl-4-chloro-7-methoxyquinoline.

What is the molecular formula and molecular weight of 4-Chloro-7-methoxy-6-quinolinecarboxamide?

4-Chloro-7-methoxy-6-quinolinecarboxamide has the molecular formula C11H9ClN2O2 and a molecular weight of 236.65 g/mol. Its IUPAC name is 4-chloro-7-methoxyquinoline-6-carboxamide.

What is 4-Chloro-7-methoxy-6-quinolinecarboxamide used for?

4-Chloro-7-methoxy-6-quinolinecarboxamide is supplied as a characterised reference material related to Lenvatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Chloro-7-methoxy-6-quinolinecarboxamide can I order?

We supply 4-Chloro-7-methoxy-6-quinolinecarboxamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Chloro-7-methoxy-6-quinolinecarboxamide?

Yes. Every lot of 4-Chloro-7-methoxy-6-quinolinecarboxamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Chloro-7-methoxy-6-quinolinecarboxamide be shipped internationally?

Yes. 4-Chloro-7-methoxy-6-quinolinecarboxamide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.