4-Amino-3-methoxybenzonitrile

Name: 4-Amino-3-methoxybenzonitrile
Brand: Vaqora Chemicals
SKU: VQ-047433

About 4-Amino-3-methoxybenzonitrile

4-Amino-3-methoxybenzonitrile (CAS 177476-76-5) is an impurity of Apremilast offered by Vaqora Chemicals. Its molecular formula is C8H8N2O and its molecular weight is 148.16 g/mol. It is also known as Benzonitrile, 4-amino-3-methoxy- or 4-amino-3-methoxybenzenecarbonitrile.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Apremilast, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 4-Amino-3-methoxybenzonitrile is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Apremilast

View every impurity, metabolite and intermediate we list for Apremilast.

Apremilast impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Amino-3-methoxybenzonitrile
Catalogue No.	VQ-047433
CAS Number	177476-76-5
IUPAC name	4-amino-3-methoxybenzonitrile
Molecular formula	C₈H₈N₂O
Molecular weight	148.16 g/mol
Exact mass	148.0637
Grade	Reference Standard
HSN code	38229090
InChIKey	SCXGWOFGMVEUGW-UHFFFAOYSA-N
SMILES	COC1=C(C=CC(=C1)C#N)N
PubChem CID	11815931

Physical properties
Physical form	Solid
LogP (XLogP3)	0.9
H-bond donors / acceptors	1 / 3
TPSA	59 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Amino-3-methoxybenzonitrile?

The CAS Registry Number of 4-Amino-3-methoxybenzonitrile is 177476-76-5. It is also known as Benzonitrile, 4-amino-3-methoxy-, 4-amino-3-methoxybenzenecarbonitrile, 4-cyano-2-methoxyaniline.

What is the molecular formula and molecular weight of 4-Amino-3-methoxybenzonitrile?

4-Amino-3-methoxybenzonitrile has the molecular formula C8H8N2O and a molecular weight of 148.16 g/mol. Its IUPAC name is 4-amino-3-methoxybenzonitrile.

What is 4-Amino-3-methoxybenzonitrile used for?

4-Amino-3-methoxybenzonitrile is supplied as a characterised reference material related to Apremilast. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Amino-3-methoxybenzonitrile can I order?

We supply 4-Amino-3-methoxybenzonitrile in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Amino-3-methoxybenzonitrile?

Yes. Every lot of 4-Amino-3-methoxybenzonitrile is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Amino-3-methoxybenzonitrile be shipped internationally?

Yes. 4-Amino-3-methoxybenzonitrile is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.