4-Chlorobenzyl Chloride

Name: 4-Chlorobenzyl Chloride
Brand: Vaqora Chemicals
SKU: VQ-032598

About 4-Chlorobenzyl Chloride

4-Chlorobenzyl Chloride (CAS 104-83-6) is a process intermediate or related compound of Pyrimethamine offered by Vaqora Chemicals. The compound has the formula C7H6Cl2, corresponding to a molecular weight of 161.03 g/mol. Its systematic (IUPAC) name is 1-chloro-4-(chloromethyl)benzene. It is also known as p,alpha-Dichlorotoluene or p-Chlorobenzyl chloride.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Process chemists and analysts use it when developing synthetic routes to Pyrimethamine, tracking process-related impurities and validating analytical methods. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 4-Chlorobenzyl Chloride is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development
Fine chemical synthesis

Industries

Related to Pyrimethamine

View every impurity, metabolite and intermediate we list for Pyrimethamine.

Pyrimethamine impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Chlorobenzyl Chloride
Catalogue No.	VQ-032598
CAS Number	104-83-6
IUPAC name	1-chloro-4-(chloromethyl)benzene
Molecular formula	C₇H₆Cl₂
Molecular weight	161.03 g/mol
Exact mass	159.9847
InChIKey	JQZAEUFPPSRDOP-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1CCl)Cl
PubChem CID	7723

Physical properties
Physical form	Solid
LogP (XLogP3)	3.2
H-bond donors / acceptors	0 / 0
TPSA	0 Å²
Synonyms	p,alpha-Dichlorotoluene, p-Chlorobenzyl chloride, alpha,4-Dichlorotoluene, Benzene, 1-chloro-4-(chloromethyl)-, (4-Chlorophenyl)methyl chloride, 1-Chloro-4-chloromethyl-benzene, alpha,p-Dichlorotoluene, p-chlorobenzylchloride, p-Chlorophenylmethyl chloride, .alpha.,p-Dichlorotoluene, .alpha.,4-Dichlorotoluene

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Environmental hazard

Signal word: Danger

Hazard statements

H302+H312+H332Harmful if swallowed, in contact with skin or if inhaled
H302Harmful if swallowed
H312Harmful in contact with skin
H314Causes severe skin burns and eye damage
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H332Harmful if inhaled
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P260, P261, P264, P264 + P265, P270, P271, P272, P273, P280, P301 + P317, P301 + P330 + P331, P302 + P352, P302 + P361 + P354, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P316, P317, P321, P330, P333 + P317, P337 + P317, P362 + P364, P363

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 104-83-6

Extra Pure

4-Chlorobenzyl chloride, extra pure >98%

CAS: 104-83-6
Formula: C₇H₆Cl₂
MW: 161.03 g/mol

VQ-020027

Frequently asked questions

What is the CAS number of 4-Chlorobenzyl Chloride?

The CAS Registry Number of 4-Chlorobenzyl Chloride is 104-83-6. It is also known as p,alpha-Dichlorotoluene, p-Chlorobenzyl chloride, alpha,4-Dichlorotoluene.

What is the molecular formula and molecular weight of 4-Chlorobenzyl Chloride?

4-Chlorobenzyl Chloride has the molecular formula C7H6Cl2 and a molecular weight of 161.03 g/mol. Its IUPAC name is 1-chloro-4-(chloromethyl)benzene.

What is 4-Chlorobenzyl Chloride used for?

4-Chlorobenzyl Chloride is supplied as a characterised reference material related to Pyrimethamine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Chlorobenzyl Chloride can I order?

We supply 4-Chlorobenzyl Chloride, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Chlorobenzyl Chloride?

Yes. Every lot of 4-Chlorobenzyl Chloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Chlorobenzyl Chloride be shipped internationally?

Yes. 4-Chlorobenzyl Chloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.